龙葵果实中的萜类化合物。

IF 1.8 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Yan Liu, Shuang Liu, Zhen-Peng Xu, Si-Yi Wang, Yi-Kai Jiang, Wei Guan, Juan Pan, Hai-Xue Kuang, Bing-You Yang
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引用次数: 0

摘要

从紫茄果实的乙醇提取物中分离鉴定出11个化合物,包括2个新化合物(1-2)和9个已知化合物(3-11)。它们的结构被确定为美洛庚烯C15-O-β-D-吡喃葡糖苷(1),(9Z)-3,7,11,15-四甲基-十六碳-1,6,10-三烯-3,5,14,15-四醇-5-O-β-D-吡喃葡糖糖苷(2),锕二苷A(3),拜占庭苷B(4),柠檬糖苷A(5),7Z玫瑰糖苷(6),matenoside A(7),大斯的曼(8),二氢相酸3'-O-β-D-,和胡樟苷C(11)。本文利用核磁共振波谱对这些化合物的结构进行了研究,并将其数据与文献中的数据进行了比较。此外,还使用脂多糖(LPS)诱导的RAW264.7细胞炎症模型评估了这些化合物的潜在抗炎活性。萜类化合物没有显示出显著的抗炎活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Terpenoid compounds from the fruits of Solanum virginianum.

Eleven compounds were isolated and identified from ethanolic extracts of Solanum virginianum fruits, including two new compounds (1-2) and nine known compounds (3-11). Their structures were determined to be melongenaterpene C15-O-β-D-glucopyranoside (1), (9Z)-3,7,11,15-tetramethyl -hexadeca-1,6,10-triene-3,5,14,15-tetraol-5-O-β-D-glucopyranoside (2), actini-dioionoside A (3), byzantionoside B (4), citroside A (5), 7Z-roseoside (6), matenoside A (7), megastigmane (8), dihydrophaseic acid 3'-O-β-D-glucopyranoside (9), taraxerol (10), and huzhangoside C (11). In this paper, NMR spectroscopy was used to study the structures of the compounds, comparing their data with those in the literature. In addition, the potential anti-inflammatory activity of the compounds was also evaluated using the RAW264.7 cell inflammation model induced by lipopolysaccharide (LPS). The terpenoids showed no significant anti-inflammatory activity.

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来源期刊
CiteScore
4.10
自引率
5.00%
发文量
55
期刊介绍: A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) is an international scientific journal and a community resource for the emerging field of natural and natural-like products. The journal publishes original research on the isolation (including structure elucidation), bio-chemical synthesis and bioactivities of natural products, their biochemistry, pharmacology, biotechnology, and their biological activity and innovative developed computational methods for predicting the structure and/or function of natural products. A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) welcomes research papers in fields on the chemistry-biology boundary which address scientific ideas and approaches to generate and understand natural compounds on a molecular level and/or use them to stimulate and manipulate biological processes.
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