对具有良好前伸能力的患者启动下颌推进装置治疗:一项随机的初步研究。

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Marie Marklund
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引用次数: 0

摘要

目的:阻塞性睡眠呼吸暂停患者对下颌前移器(MAD)的接受度差与不适有关。本研究比较了具有良好前伸能力的患者下颌前移程度较小和较大时的严重初始副作用。方法:在一项平行设计的试点研究中,连续患有阻塞性睡眠呼吸暂停且具有良好的前伸能力(≥8mm)的患者被随机分配开始治疗,下颌骨前移最大前伸量的70%(Adv70%)或4mm(Adv4mm)。主要结果是使用0-10视觉模拟评分(VAS)(从“完全不”到“非常广泛”)或在治疗的第一周因副作用而排除使用牙齿或颌骨的压痛或疼痛。次要结果包括流涎问题和咬合变化。结果:18名患者被随机选择,17名患者符合研究方案。Adv70%组中有4名患者和Adv4mm组中没有一名患者在7天中的5天或5天以上出现严重压痛或疼痛(VAS≥7)(p=0.03)。下颌前移程度(以毫米为单位)与出现严重副作用的天数相关,r=0.64(p=0.006)。次要副作用较小。结论:在这项初步研究中,对于具有良好前伸能力的患者,在治疗的第一周,以70%的下颌前移开始MAD治疗与较小的固定毫米值相比,会产生更严重的副作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Starting Mandibular Advancement Device Therapy in Patients with Good Protrusive Capacity: A Randomized Pilot Study.

Starting Mandibular Advancement Device Therapy in Patients with Good Protrusive Capacity: A Randomized Pilot Study.

Starting Mandibular Advancement Device Therapy in Patients with Good Protrusive Capacity: A Randomized Pilot Study.

Starting Mandibular Advancement Device Therapy in Patients with Good Protrusive Capacity: A Randomized Pilot Study.

Objective: Discomfort has been related to the poor acceptance of a mandibular advancement device (MAD) in patients with obstructive sleep apnea. The present study compared severe initial side effects between a smaller and a larger degree of mandibular advancement in patients with a good protrusive capacity.

Methods: Consecutive patients with obstructive sleep apnea and a good protrusive capacity (≥8 mm) were randomized to start treatment with the mandible advanced by either 70% of maximum protrusion (Adv70%) or by 4 mm (Adv4mm) in a pilot study with a parallel design. The main outcome was tenderness or pain in the teeth or jaws using a 0-10 visual analogue scale (VAS) (from "not at all" to "very extensive") or excluded use because of side effects during the first week of treatment. Secondary outcomes included salivation problems and bite changes.

Results: Eighteen patients were randomly selected and 17 patients fulfilled the study protocol. Four patients in the Adv70% group and none in the Adv4mm group reported severe tenderness or pain (VAS ≥7) on five or more of the seven days (p=0.03). The degree of mandibular advancement measured in millimeters correlated with the number of days with severe side effects, r=0.64 (p=0.006). The secondary side effects were minor.

Conclusion: Starting MAD treatment with 70% mandibular advancement was related to more severe side effects during the first week of treatment compared with a smaller fixed millimeter value in patients with a good protrusive capacity in this pilot study.

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来源期刊
Turkish Journal of Orthodontics
Turkish Journal of Orthodontics Dentistry-Orthodontics
CiteScore
2.10
自引率
9.10%
发文量
34
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