532nm和660nm激光在不同组织类型中波长相关穿透深度的比较。

IF 1.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal of lasers in medical sciences Pub Date : 2023-08-29 eCollection Date: 2023-01-01 DOI:10.34172/jlms.2023.28
Ali A Aldalawi, Nursakinah Suardi, Naser Mahmoud Ahmed, Mahdi A S Al-Farawn, Mohammed Ali Dheyab, Wisam I Jebur, Faisal J Kadhim
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引用次数: 0

摘要

引言:激光穿透组织的深度是决定光动力疗法(PDT)有效性的关键因素。然而,在PDT中实现最大治疗效果所需的最佳激光穿透深度仍不清楚。本研究旨在评估激光在532 nm和660 mm两个特定波长下穿透深度的有效性。方法:使用不同厚度(1、3、5、10和20 mm±0.2 mm)的鸡肉和牛肉作为体外组织模型。样品在连续模式下经受532和660nm的低电平激光二极管的照射10分钟。功率密度分别为167和142J/cm2。使用功率计测量通过组织的激光透射。结果:对于牛肉样品,660nm波长在1cm厚度处实现了30.7%的最大透射强度,而532nm激光的透射强度为6.5%。类似地,在鸡胸肉样品中,最大透射发生在1cm厚处,660 nm波长为68.1%,532nm激光为18.2%。结论:结果一致显示出显著的相关性(P
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of Wavelength-Dependent Penetration Depth of 532 nm and 660 nm Lasers in Different Tissue Types.

Introduction: The depth of laser light penetration into tissue is a critical factor in determining the effectiveness of photodynamic therapy (PDT). However, the optimal laser light penetration depth necessary for achieving maximum therapeutic outcomes in PDT remains unclear. This study aimed to assess the effectiveness of laser light penetration depth at two specific wavelengths, 532 nm and 660 mm. Methods: Chicken and beef of different thicknesses (1, 3, 5, 10, and 20 mm±0.2 mm) were used as in vitro tissue models. The samples were subjected to irradiation by a low-level laser diode of 532 and 660 nm in continuous mode for 10 minutes. with power densities of 167 and 142 J/cm2, respectively. Laser light transmission through the tissue was measured using a power meter. Results: For beef samples, the 660 nm wavelength achieved a maximum transmission intensity of 30.7% at 1 cm thickness, while the 532 nm laser had a transmission intensity of 6.5%. Similarly, in chicken breast samples, the maximum transmission occurred at 1 cm thickness with 68.1% for the 660 nm wavelength and 18.2% for the 532 nm laser. Conclusion: Results consistently demonstrated a significant correlation (P<0.05) between tissue thickness and laser light penetration. Thicker tissues exhibited faster declines in light transmission intensity compared to thinner tissues within 10 minutes. These findings highlight the importance of further research to enhance light delivery in thicker tissues and improve the efficacy of PDT in various medical conditions.

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来源期刊
Journal of lasers in medical sciences
Journal of lasers in medical sciences RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
3.00
自引率
13.30%
发文量
24
期刊介绍: The "Journal of Lasers in Medical Sciences " is a scientific quarterly publication of the Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences. This journal received a scientific and research rank from the national medical publication committee. This Journal accepts original papers, review articles, case reports, brief reports, case series, photo assays, letters to the editor, and commentaries in the field of laser, or light in any fields of medicine such as the following medical specialties: -Dermatology -General and Vascular Surgery -Oncology -Cardiology -Dentistry -Urology -Rehabilitation -Ophthalmology -Otorhinolaryngology -Gynecology & Obstetrics -Internal Medicine -Orthopedics -Neurosurgery -Radiology -Pain Medicine (Algology) -Basic Sciences (Stem cell, Cellular and Molecular application and physic)
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