精准医学药物基因组学测试的实施。

IF 6.6 2区医学 Q1 MEDICAL LABORATORY TECHNOLOGY

Critical reviews in clinical laboratory sciences Pub Date : 2024-03-01 Epub Date: 2023-09-30 DOI:10.1080/10408363.2023.2255279

Anastasia L Gant Kanegusuku, Clarence W Chan, Peter H O'Donnell, Kiang-Teck J Yeo

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引用次数: 0

摘要

在过去的十年里，在降低临床药物基因组学实施的障碍方面取得了长足的进步。尽管如此，在开具治疗处方之前进行PGx咨询还不是主流。这篇综述探讨了当前围绕PGx实施的气候，主要关注学术机构，特别是芝加哥大学的实施策略，并提供了支持PGx项目开发的最新资源指南。讨论了剩余的挑战以及克服这些执行挑战的最新战略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Implementation of pharmacogenomics testing for precision medicine.

Great strides have been made in the past decade to lower barriers to clinical pharmacogenomics implementation. Nevertheless, PGx consultation prior to prescribing therapeutics is not yet mainstream. This review addresses the current climate surrounding PGx implementation, focusing primarily on strategies for implementation at academic institutions, particularly at The University of Chicago, and provides an up-to-date guide of resources supporting the development of PGx programs. Remaining challenges and recent strategies for overcoming these challenges to implementation are discussed.

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来源期刊

Critical reviews in clinical laboratory sciences 医学-医学实验技术

CiteScore

20.00

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Critical Reviews in Clinical Laboratory Sciences publishes comprehensive and high quality review articles in all areas of clinical laboratory science, including clinical biochemistry, hematology, microbiology, pathology, transfusion medicine, genetics, immunology and molecular diagnostics. The reviews critically evaluate the status of current issues in the selected areas, with a focus on clinical laboratory diagnostics and latest advances. The adjective “critical” implies a balanced synthesis of results and conclusions that are frequently contradictory and controversial.