锰催化脱氢偶联反应合成噻吩取代酮。

IF 3.5 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemistry - An Asian Journal Pub Date : 2023-10-03 DOI:10.1002/asia.202300725

Xiaoyu Zhang, Yujie Zhang, Jiaqiao Ding, Liusheng Wang, Weihua Chen, Xinyan Li, Dr. Bing Cui, Prof. Mingqin Zhao, Dr. Zhihui Shao

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引用次数: 0

摘要

本研究报道了一种以2-噻吩甲醇和酮为原料，以锰络合物为催化剂，通过脱氢偶联合成噻吩取代酮的高效绿色一步法。锰络合物在温和条件下表现出广泛的适用性，并扩大了可用基质的范围。利用这一策略，我们进行了酮与2-噻吩甲醇的高效多样的反应，并以良好的分离产率成功合成了一系列噻吩取代的饱和酮和α，β-不饱和酮。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Synthesis of Thiophene-Substituted Ketones via Manganese-Catalyzed Dehydrogenative Coupling Reaction

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Synthesis of Thiophene-Substituted Ketones via Manganese-Catalyzed Dehydrogenative Coupling Reaction

This study reports an efficient and green one-step method for synthesizing thiophene-substituted ketones from 2-thiophenemethanol and ketones via dehydrogenative coupling using manganese complexes as catalysts. The manganese complex demonstrated a broad applicability under mild conditions and extended the range of usable substrates. Utilizing this strategy, we carried out an efficient and diverse reaction of ketones with 2-thiophenemethanol, and successfully synthesized a series of thiophene-substituted saturated ketones and α, β-unsaturated ketones in good isolated yields.

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来源期刊

Chemistry - An Asian Journal 化学-化学综合

CiteScore

7.00

自引率

2.40%

发文量

535

审稿时长

1.3 months

期刊介绍： Chemistry—An Asian Journal is an international high-impact journal for chemistry in its broadest sense. The journal covers all aspects of chemistry from biochemistry through organic and inorganic chemistry to physical chemistry, including interdisciplinary topics. Chemistry—An Asian Journal publishes Full Papers, Communications, and Focus Reviews. A professional editorial team headed by Dr. Theresa Kueckmann and an Editorial Board (headed by Professor Susumu Kitagawa) ensure the highest quality of the peer-review process, the contents and the production of the journal. Chemistry—An Asian Journal is published on behalf of the Asian Chemical Editorial Society (ACES), an association of numerous Asian chemical societies, and supported by the Gesellschaft Deutscher Chemiker (GDCh, German Chemical Society), ChemPubSoc Europe, and the Federation of Asian Chemical Societies (FACS).