含有碱基-芳香环共轭物的寡脱氧核糖核苷酸的螺旋形成。

Mio Kubota, Momo Kosuge, Akira Ono
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引用次数: 0

摘要

新的核苷类似物的碱基部分含有芘基团已被合成并纳入到寡脱氧核糖核苷酸(ODNs)。在5'端含有串联芘残基的odn具有荧光光谱特征,这种荧光光谱特征由于odn与互补链的双工形成而减弱。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Helix formation of oligodeoxyribonucleotides containing base-aromatic ring conjugates.

Novel nucleoside analogues with base moieties containing pyrene groups have been synthesized and incorporated into oligodeoxyribonucleotides (ODNs). ODNs containing tandem pyrene residues at the 5'-end gave fluorescence spectra characteristic of eximers that were diminished by duplex formation of the ODNs with complementary strands.

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