{"title":"四向结DNA的体外筛选。","authors":"Tomomitsu Ozeki, Hiroyuki Furusawa, Yoshio Okahata","doi":"10.1093/nass/3.1.257","DOIUrl":null,"url":null,"abstract":"<p><p>We could obtain the DNA aptamers that can bind strongly and selectively to ATP (Ka = 6.7 x 10(7) M(-1)) from four way junction random DNAs by using in vitro selection on a quartz-crystal microbalance.</p>","PeriodicalId":86149,"journal":{"name":"Nucleic acids research. Supplement (2001)","volume":" 3","pages":"257-8"},"PeriodicalIF":0.0000,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/nass/3.1.257","citationCount":"0","resultStr":"{\"title\":\"In vitro selection of four way junction DNA.\",\"authors\":\"Tomomitsu Ozeki, Hiroyuki Furusawa, Yoshio Okahata\",\"doi\":\"10.1093/nass/3.1.257\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We could obtain the DNA aptamers that can bind strongly and selectively to ATP (Ka = 6.7 x 10(7) M(-1)) from four way junction random DNAs by using in vitro selection on a quartz-crystal microbalance.</p>\",\"PeriodicalId\":86149,\"journal\":{\"name\":\"Nucleic acids research. Supplement (2001)\",\"volume\":\" 3\",\"pages\":\"257-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2003-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1093/nass/3.1.257\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nucleic acids research. Supplement (2001)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/nass/3.1.257\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nucleic acids research. Supplement (2001)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/nass/3.1.257","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
在石英晶体微天平上进行体外筛选，从四向结随机DNA中获得了能与ATP (Ka = 6.7 x 10(7) M(-1))强选择性结合的核酸适体。
We could obtain the DNA aptamers that can bind strongly and selectively to ATP (Ka = 6.7 x 10(7) M(-1)) from four way junction random DNAs by using in vitro selection on a quartz-crystal microbalance.
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