Boadie W. Dunlop , Jeffrey J. Rakofsky , David Mischoulon , Helen S. Mayberg , Becky Kinkead , Andrew A. Nierenberg , Thomas R. Ziegler , Maurizio Fava , Mark H. Rapaport
{"title":"美国个人社会经济剥夺指数(USiDep)","authors":"Boadie W. Dunlop , Jeffrey J. Rakofsky , David Mischoulon , Helen S. Mayberg , Becky Kinkead , Andrew A. Nierenberg , Thomas R. Ziegler , Maurizio Fava , Mark H. Rapaport","doi":"10.1016/j.pmip.2022.100091","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Individuals experiencing socioeconomic deprivation consistently demonstrate poorer physical and mental health. Income alone is inadequate as a measure of socioeconomic status (SES); a better measure for assessing the deprivation status of individuals is needed.</p></div><div><h3>Methods</h3><p>The New Zealand Index of Socioeconomic Deprivation for Individuals, a validated, eight-item measure of deprivation, was modified to create the United States Index of Socioeconomic Deprivation for Individuals (USiDep). The questionnaire was administered to patients with major depressive disorder participating in two clinical trials. Spearman’s correlation coefficients evaluated associations between USiDep scores with income and other measures associated with deprivation.</p></div><div><h3>Results</h3><p>The USiDep was completed by 118 participants, demonstrating adequate internal consistency (Crohnbach’s alpha = 0.766) and strong item-total correlations. USiDep scores were moderately correlated with past-year personal income (Spearman’s rho = -0.362, p < .001) and several other measures related to deprivation, including body mass index, level of education, quality of life, severity of childhood traumatic events, self-reported physical health, and negative life events. Patients scoring 5 on the USiDep (the highest possible score, indicating greater deprivation) had significantly lower rates of remission after 12 weeks of treatment than those scoring ≤ 4 (1/12, 8.3% vs 40/98, 40.8%, respectively, p = .03), whereas the lowest income group showed no significant associations with outcomes.</p></div><div><h3>Conclusion</h3><p>The USiDep is a valid, brief questionnaire for assessing SES that has utility for clinical research and may serve as a predictor of treatment outcomes in clinical trials. Validation of the USiDep in healthy controls and other medically and psychiatrically ill populations is warranted.</p></div>","PeriodicalId":19837,"journal":{"name":"Personalized Medicine in Psychiatry","volume":"31 ","pages":"Article 100091"},"PeriodicalIF":0.0000,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/71/a0/nihms-1771841.PMC9355266.pdf","citationCount":"3","resultStr":"{\"title\":\"The United States index of socioeconomic deprivation for individuals (USiDep)\",\"authors\":\"Boadie W. Dunlop , Jeffrey J. Rakofsky , David Mischoulon , Helen S. Mayberg , Becky Kinkead , Andrew A. Nierenberg , Thomas R. Ziegler , Maurizio Fava , Mark H. Rapaport\",\"doi\":\"10.1016/j.pmip.2022.100091\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Individuals experiencing socioeconomic deprivation consistently demonstrate poorer physical and mental health. Income alone is inadequate as a measure of socioeconomic status (SES); a better measure for assessing the deprivation status of individuals is needed.</p></div><div><h3>Methods</h3><p>The New Zealand Index of Socioeconomic Deprivation for Individuals, a validated, eight-item measure of deprivation, was modified to create the United States Index of Socioeconomic Deprivation for Individuals (USiDep). The questionnaire was administered to patients with major depressive disorder participating in two clinical trials. Spearman’s correlation coefficients evaluated associations between USiDep scores with income and other measures associated with deprivation.</p></div><div><h3>Results</h3><p>The USiDep was completed by 118 participants, demonstrating adequate internal consistency (Crohnbach’s alpha = 0.766) and strong item-total correlations. USiDep scores were moderately correlated with past-year personal income (Spearman’s rho = -0.362, p < .001) and several other measures related to deprivation, including body mass index, level of education, quality of life, severity of childhood traumatic events, self-reported physical health, and negative life events. Patients scoring 5 on the USiDep (the highest possible score, indicating greater deprivation) had significantly lower rates of remission after 12 weeks of treatment than those scoring ≤ 4 (1/12, 8.3% vs 40/98, 40.8%, respectively, p = .03), whereas the lowest income group showed no significant associations with outcomes.</p></div><div><h3>Conclusion</h3><p>The USiDep is a valid, brief questionnaire for assessing SES that has utility for clinical research and may serve as a predictor of treatment outcomes in clinical trials. Validation of the USiDep in healthy controls and other medically and psychiatrically ill populations is warranted.</p></div>\",\"PeriodicalId\":19837,\"journal\":{\"name\":\"Personalized Medicine in Psychiatry\",\"volume\":\"31 \",\"pages\":\"Article 100091\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/71/a0/nihms-1771841.PMC9355266.pdf\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Personalized Medicine in Psychiatry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2468171722000011\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Personalized Medicine in Psychiatry","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2468171722000011","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
摘要
经历社会经济剥夺的个体始终表现出较差的身心健康。收入本身不足以衡量社会经济地位(SES);需要一种更好的措施来评估个人的贫困状况。方法对新西兰个人社会经济剥夺指数进行修改,创建美国个人社会经济剥夺指数(USiDep)。该问卷被用于参与两项临床试验的重度抑郁症患者。斯皮尔曼的相关系数评估了USiDep得分与收入和其他与剥夺相关的指标之间的关系。结果USiDep有118名参与者完成,显示出足够的内部一致性(Crohnbach 's alpha = 0.766)和很强的项目-总量相关性。USiDep得分与过去一年的个人收入呈正相关(Spearman’s rho = -0.362, p <.001)和其他一些与剥夺相关的指标,包括体重指数、教育水平、生活质量、童年创伤事件的严重程度、自我报告的身体健康状况和负面生活事件。USiDep得分为5分的患者(最高可能得分,表明剥夺程度更大)在12周治疗后的缓解率明显低于得分≤4分的患者(1/ 12,8.3% vs 40/ 98,40.8%,分别p = 0.03),而最低收入组与结果无显著关联。结论USiDep是一份有效的、简短的SES评估问卷,对临床研究具有实用价值,可作为临床试验治疗结果的预测指标。在健康对照和其他医学和精神疾病人群中验证USiDep是有必要的。
The United States index of socioeconomic deprivation for individuals (USiDep)
Background
Individuals experiencing socioeconomic deprivation consistently demonstrate poorer physical and mental health. Income alone is inadequate as a measure of socioeconomic status (SES); a better measure for assessing the deprivation status of individuals is needed.
Methods
The New Zealand Index of Socioeconomic Deprivation for Individuals, a validated, eight-item measure of deprivation, was modified to create the United States Index of Socioeconomic Deprivation for Individuals (USiDep). The questionnaire was administered to patients with major depressive disorder participating in two clinical trials. Spearman’s correlation coefficients evaluated associations between USiDep scores with income and other measures associated with deprivation.
Results
The USiDep was completed by 118 participants, demonstrating adequate internal consistency (Crohnbach’s alpha = 0.766) and strong item-total correlations. USiDep scores were moderately correlated with past-year personal income (Spearman’s rho = -0.362, p < .001) and several other measures related to deprivation, including body mass index, level of education, quality of life, severity of childhood traumatic events, self-reported physical health, and negative life events. Patients scoring 5 on the USiDep (the highest possible score, indicating greater deprivation) had significantly lower rates of remission after 12 weeks of treatment than those scoring ≤ 4 (1/12, 8.3% vs 40/98, 40.8%, respectively, p = .03), whereas the lowest income group showed no significant associations with outcomes.
Conclusion
The USiDep is a valid, brief questionnaire for assessing SES that has utility for clinical research and may serve as a predictor of treatment outcomes in clinical trials. Validation of the USiDep in healthy controls and other medically and psychiatrically ill populations is warranted.