伴有和不伴有神经介导性晕厥的患者的同时搏动心率和收缩压变异性。

IF 1.2 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Amirhossein Akbarzadeh, Fariborz Akbarzadeh, Babak Kazemi
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引用次数: 0

摘要

导语:自主神经改变在神经介导性晕厥(NMS)的发生中起重要作用。本研究的目的是比较自主神经系统(ANS)的变化,通过测量频谱指数搏动收缩压和心率变异性(SBPV和HRV)在低频(LF),高频(HF)和LF/HF比值在平视倾斜试验(HUTT)中有和没有晕厥反应的患者。方法:对46例怀疑有不明原因晕厥病史的患者进行病例对照研究,分别记录HUTT典型的三个阶段的数据。发生晕厥的患者被指定为病例组,其余为对照组。结果:31例患者在HUTT期间出现晕厥。静息HRV和SBPV指数明显低于对照组。晕厥组倾斜后,SBPV的HF和LF功率均呈明显的逐渐下降。两组HRV的LF/HF在试验期间增加相似,但在SBPV中,主要由LF功率的振荡驱动,它在晕厥患者试验的前两个阶段显著增加,但在主动倾斜期间反而下降(P< 0.001)。结论:我们的研究结果显示晕厥患者在休息和倾斜时都有异常的自主神经功能。作为一种潜在的纯交感神经活动的新指标,搏动-搏动SBPV的频谱指数波动在倾斜和晕厥前退出时表现出夸张的反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Simultaneous beat-to-beat heart rate and systolic blood pressure variability in patients with and without neurally mediated syncope.

Simultaneous beat-to-beat heart rate and systolic blood pressure variability in patients with and without neurally mediated syncope.

Simultaneous beat-to-beat heart rate and systolic blood pressure variability in patients with and without neurally mediated syncope.

Simultaneous beat-to-beat heart rate and systolic blood pressure variability in patients with and without neurally mediated syncope.

Introduction: Autonomic changes play an essential role in the genesis of neurally mediated syncope (NMS). The aim of this study was to compare the changes of the autonomic nervous system (ANS) by measuring spectral indices of beat-to-beat systolic blood pressure and heart rate variability (SBPV and HRV) in ranges of low frequency (LF), high frequency (HF), and the LF/HF ratio during head-up tilt test (HUTT) in patients with and without a syncope response. Methods: In this case-control study of 46 patients with a suspected history of unexplained syncope, data were recorded separately during the typical three phases of HUTT. Patients who developed syncope were designated as the case group and the rest as the control group. Results: Thirty one patients experienced syncope during HUTT. Resting HRV and SBPV indices were significantly lower in cases than controls. After tilting in the syncope group, both HF and LF powers of SBPV showed a significant and gradual decrease. LF/HF in HRV increased in both groups similarly during the test but in SBPV, mainly driven by oscilations in its LF power, it increased significantly more during the first two phases of the test in syncope patients only to paradoxically decrease during active tilt (P< 0.001). Conclusion: Our findings show an abnormal autonomic function in patients with syncope, both at rest and tilting. Fluctuations of spectral indices of beat-to-beat SBPV, a potential noval index of pure sympathetic activity, show an exaggerated response during tilt and its withdrawal before syncope.

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来源期刊
Journal of Cardiovascular and Thoracic Research
Journal of Cardiovascular and Thoracic Research CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.00
自引率
0.00%
发文量
22
审稿时长
7 weeks
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