The Co-Administration of COVID-19 and Hepatitis B Vaccines, Should Safety Be a Concern?

We read with great interest the recent contribution by Choi and Cheong entitled “Should the COVID-19 Vaccine be Administered Simultaneously with Other Vaccines?” [1]. The topic of concomitant administration of coronavirus disease 2019 (COVID-19) and other vaccines has been largely overlooked in literature and hence the available data represent general recommendations and guidelines that need to be carefully applied. The editorial by Choi and Cheong clearly underscores the importance of considering the current health status of the individual to receive the vaccines as well as the specifications of each vaccine to be administered. The authors also overviewed the different protocols currently applied in some countries as well as the World Health Organization recommendations. Apparently, two major concerns are to be addressed about the concomitant administration of COVID-19 and other vaccines: potential adverse reactions and immunogenicity, i.e., safety and efficacy.