部分肾切除术治疗T1b/T2肾肿块:与根治性肾切除术相比的一个额外转移。

IF 1.9 Q3 ONCOLOGY
Journal of Kidney Cancer and VHL Pub Date : 2022-10-06 eCollection Date: 2022-01-01 DOI:10.15586/jkcvhl.v9i4.255
Mohamed Sharafeldeen, Wael Sameh, Vahid Mehrnoush, Amer Alaref, Radu Rozenberg, Asmaa Ismail, Hazem Elmansy, Walid Shahrour, Ahmed Zakaria, Osama Elmeslemany, Nishigandha Burute, Anatoly Shuster, Owen Prowse, Ahmed Kotb
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引用次数: 1

摘要

我们研究的目的是展示我们在过去3年中通过部分肾切除术(PN)治疗大肾肿块(cT1b/T2)的短期经验。回顾性收集过去3年中所有肾肿块大于4cm的患者的数据。收集流行病学资料。收集手术资料,包括手术时间、缺血时间、术中及术后并发症。收集术前和术后估计肾小球滤过率(eGFR)数据,并将其与术后并发症和复发进行关联。我们发现47例经放射学证实>4 cm的肾肿块采用PN治疗。患者平均年龄55.7±13.4岁,其中男性29例,女性18例。40例肿块位于T1b, 7例肿块位于T2。肿瘤平均大小为6.2±1.5 cm。采用肾肾测量评分法;8、28和11分别具有低、中等和高的复杂性。肾细胞癌(RCC)确诊42例。42例癌性病例中有5例(12%)为病理性T3 RCC。术前、术后平均eGFR分别为89.09±12.41、88.50±10.50 (P < 0.2)。中位随访时间为14个月,在这么短的时间内,没有患者出现癌症复发的迹象。对于大的肾肿块,在经验丰富的人手中是安全的,无论肿瘤的复杂性如何,应该在更高比例的患者中尝试PN。在我们的短期随访中没有观察到癌症复发或肾功能恶化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Partial Nephrectomy for T1b/T2 Renal Mass: An Added Shift from Radical Nephrectomy.

Partial Nephrectomy for T1b/T2 Renal Mass: An Added Shift from Radical Nephrectomy.

Partial Nephrectomy for T1b/T2 Renal Mass: An Added Shift from Radical Nephrectomy.

Partial Nephrectomy for T1b/T2 Renal Mass: An Added Shift from Radical Nephrectomy.

The aim of our study was to show our short-term experience in managing large renal masses (cT1b/T2) through partial nephrectomy (PN) over the last 3 years. Retrospective data collection for all patients managed by PN for renal masses larger than 4 cm over the last 3 years. Epidemiological data were collected. Surgical data including surgical and ischemic times as well as intra and postoperative complications were collected. Pre- and postoperative estimated glomerular filtration rate (eGFR) data were collected and correlated as well as postoperative complications and recurrence. We could identify 47 patients managed by PN for radiologically confirmed >4 cm renal masses. The mean age of the patients was 55.7 ± 13.4, including 29 males and 18 females. Masses were T1b and T2 in 40 and 7 patients, respectively. The mean tumor size was 6.2 ± 1.5 cm. Using renal nephrometry score; 8, 28, and 11 had low, moderate, and high complexity, respectively. Renal cell carcinoma (RCC) was identified in 42 patients. Five patients out of 42 cancerous cases (12%) had pathological T3 RCC. The mean preoperative and postoperative eGFR were 89.09 ± 12.41 and 88.50 ± 10.50, respectively (P 0.2). The median follow-up was 14 months and within that short time, no patient had evidence for cancer recurrence. PN for large renal masses is safe in experienced hands and should be attempted in a higher percentage of patients, regardless of the tumor complexity. No cancer recurrence or deterioration of renal function was observed within our short-term follow-up.

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6.20%
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审稿时长
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