3d打印微流体在对抗未来和当前流行病(COVID-19)中的潜力。

Heba A Eassa, Nada A Helal, Ahmed M Amer, Aliaa Fouad, Asser F Bedair, Reem Nagib, Ihab Mansoor, Motaz Hawash, Maha Abdul-Latif, Kamilia H A Mohammed, Mohamed A Helal, Mohamed Ismail Nounou
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引用次数: 1

摘要

2019年12月,中国出现新型冠状病毒病(COVID-19)。2020年3月,世界卫生组织宣布其为大流行,导致全球封锁和旅行限制。到5月,感染人数为4,789,205人,死亡人数为318,789人。这除了造成毁灭性的社会经济影响外,还导致医疗部门严重短缺。人工智能(AI)、虚拟现实(VR)、微流体、3D打印、3D扫描等许多技术都可以介入遏制病毒并阻止其广泛传播。本文旨在探讨3D打印和微流控技术在加速疾病诊断和监测以及弥补个人防护装备和医疗设备短缺方面的潜力。它强调了3D打印机和微流体在提供个人防护装备(口罩、呼吸器、面罩、护目镜和隔离室/头罩)、支持性护理(呼吸设备)和诊断用品(取样拭子和芯片实验室)方面的主要应用,以缓解COVID-19的压力。此外,还讨论了此类技术的成本和监管方面的考虑。我们的结论是,3D打印提供了可重复使用和低成本的解决方案,以缓解短缺。然而,安全性、无菌性和与环保标准的兼容性需要通过监管机构的标准化和评估来保证。最后,从这次大流行中吸取的教训也可以帮助世界为即将到来的疫情做好准备。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
3D-Printed Microfluidics Potential in Combating Future and Current Pandemics (COVID-19).

Coronavirus disease (COVID-19) emerged in China in December 2019. In March 2020, the WHO declared it a pandemic leading to worldwide lockdowns and travel restrictions. By May, it infected 4,789,205 and killed 318,789 people. This led to severe shortages in the medical sector besides devastating socio-economic effects. Many technologies such as artificial intelligence (AI), virtual reality (VR), microfluidics, 3D printing, and 3D scanning can step into contain the virus and hinder its extensive spread. This article aims to explore the potentials of 3D printing and microfluidic in accelerating the diagnosis and monitoring of the disease and fulfilling the shortages of personal protective equipment (PPE) and medical equipment. It highlights the main applications of 3D printers and microfluidics in providing PPE (masks, respirators, face shields, goggles, and isolation chambers/hoods), supportive care (respiratory equipment) and diagnostic supplies (sampling swabs & lab-on-chip) to ease the COVID-19 pressures. Also, the cost of such technology and regulation considerations are addressed. We conclude that 3D printing provided reusable and low-cost solutions to mitigate the shortages. However, safety, sterility, and compatibility with environmental protection standards need to be guaranteed through standardization and assessment by regulatory bodies. Finally, lessons learned from this pandemic can also help the world prepare for upcoming outbreaks.

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