{"title":"增强幸福感与甲状腺毒症相关:甲状腺激素的忽视作用?","authors":"Petros Perros, Laszlo Hegedus","doi":"10.5812/ijem-127230","DOIUrl":null,"url":null,"abstract":"<p><strong>Context: </strong>Thyrotoxicosis may be associated with a better sense of well-being than in the euthyroid state, though this is not widely recognised.</p><p><strong>Evidence acquisition: </strong>A comprehensive literature search in PubMed and Google Scholar, was performed to identify studies investigating factors influencing well-being, mood, and psychological features associated with elevated thyroid hormones.</p><p><strong>Results: </strong>Enhanced well-being associated with thyrotoxicosis has been described, although the evidence is observational and anecdotal.</p><p><strong>Conclusions: </strong>Enhanced well-being associated with thyrotoxicosis is probably experienced in a minority of patients and may explain why some seek overtreatment with thyroid hormones and report significant improvement on larger than physiological thyroid hormone replacement regimens. It may also explain why some patients with hyperthyroidism (usually due to Graves' disease) are reluctant to adhere to anti-thyroid medication.</p>","PeriodicalId":13969,"journal":{"name":"International Journal of Endocrinology and Metabolism","volume":"20 2","pages":"e127230"},"PeriodicalIF":2.1000,"publicationDate":"2022-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/da/14/ijem-20-2-127230.PMC9375936.pdf","citationCount":"0","resultStr":"{\"title\":\"Enhanced Well-Being Associated with Thyrotoxicosis: A Neglected Effect of Thyroid Hormones?\",\"authors\":\"Petros Perros, Laszlo Hegedus\",\"doi\":\"10.5812/ijem-127230\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Context: </strong>Thyrotoxicosis may be associated with a better sense of well-being than in the euthyroid state, though this is not widely recognised.</p><p><strong>Evidence acquisition: </strong>A comprehensive literature search in PubMed and Google Scholar, was performed to identify studies investigating factors influencing well-being, mood, and psychological features associated with elevated thyroid hormones.</p><p><strong>Results: </strong>Enhanced well-being associated with thyrotoxicosis has been described, although the evidence is observational and anecdotal.</p><p><strong>Conclusions: </strong>Enhanced well-being associated with thyrotoxicosis is probably experienced in a minority of patients and may explain why some seek overtreatment with thyroid hormones and report significant improvement on larger than physiological thyroid hormone replacement regimens. It may also explain why some patients with hyperthyroidism (usually due to Graves' disease) are reluctant to adhere to anti-thyroid medication.</p>\",\"PeriodicalId\":13969,\"journal\":{\"name\":\"International Journal of Endocrinology and Metabolism\",\"volume\":\"20 2\",\"pages\":\"e127230\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2022-05-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/da/14/ijem-20-2-127230.PMC9375936.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Endocrinology and Metabolism\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.5812/ijem-127230\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/4/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Endocrinology and Metabolism","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5812/ijem-127230","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/4/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
Enhanced Well-Being Associated with Thyrotoxicosis: A Neglected Effect of Thyroid Hormones?
Context: Thyrotoxicosis may be associated with a better sense of well-being than in the euthyroid state, though this is not widely recognised.
Evidence acquisition: A comprehensive literature search in PubMed and Google Scholar, was performed to identify studies investigating factors influencing well-being, mood, and psychological features associated with elevated thyroid hormones.
Results: Enhanced well-being associated with thyrotoxicosis has been described, although the evidence is observational and anecdotal.
Conclusions: Enhanced well-being associated with thyrotoxicosis is probably experienced in a minority of patients and may explain why some seek overtreatment with thyroid hormones and report significant improvement on larger than physiological thyroid hormone replacement regimens. It may also explain why some patients with hyperthyroidism (usually due to Graves' disease) are reluctant to adhere to anti-thyroid medication.
期刊介绍：
The aim of the International Journal of Endocrinology and Metabolism (IJEM) is to increase knowledge, stimulate research in the field of endocrinology, and promote better management of patients with endocrinological disorders. To achieve this goal, the journal publishes original research papers on human, animal and cell culture studies relevant to endocrinology.
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