Lucy Honeycutt, Katherine Huerne, Alanna Miller, Erica Wennberg, Kristian B Filion, Roland Grad, Andrea S Gershon, Carolyn Ells, Genevieve Gore, Andrea Benedetti, Brett Thombs, Mark J Eisenberg
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引用次数: 4
摘要
鉴于电子烟的使用越来越多,以及围绕其安全性的不确定性,我们进行了一项系统综述,以确定电子烟对肺功能测量的影响。从2004年到2021年7月,我们通过Ovid、Cochrane CENTRAL数据库和Web of Science Core系统地检索了EMBASE、MEDLINE和PsycINFO数据库,确定了8856项潜在的符合条件的研究。共纳入了8项研究(7项研究即时影响,1项研究长期影响,共273名参与者)。使用非随机干预研究的偏倚风险(ROBINS-I)和Cochrane偏倚风险工具评估偏倚风险。这些研究表明,电子烟会增加气道阻力,但似乎不会影响一秒钟用力呼气量(FEV1)、用力肺活量(FVC)或FEV1/FVC比率。然而,鉴于这些研究的规模和随访时间有限,需要更大规模的长期研究来进一步确定电子烟对肺功能的影响。
A systematic review of the effects of e-cigarette use on lung function.
Given the increasing use of e-cigarettes and uncertainty surrounding their safety, we conducted a systematic review to determine the effects of e-cigarettes on measures of lung function. We systematically searched EMBASE, MEDLINE, and PsycINFO databases via Ovid, the Cochrane CENTRAL database, and the Web of Science Core from 2004 until July 2021, identifying 8856 potentially eligible studies. A total of eight studies (seven studying immediate effects and one long-term effects, 273 total participants) were included. The risk of bias was assessed using the Risk of Bias in Non-randomized Studies-of Interventions (ROBINS-I) and Cochrane risk of bias tools. These studies suggest that vaping increases airway resistance but does not appear to impact forced expiratory volume in one second (FEV1), forced vital capacity (FVC), or FEV1/FVC ratio. However, given the limited size and follow-up duration of these studies, larger, long-term studies are required to further determine the effects of e-cigarettes on lung function.
期刊介绍:
npj Primary Care Respiratory Medicine is an open access, online-only, multidisciplinary journal dedicated to publishing high-quality research in all areas of the primary care management of respiratory and respiratory-related allergic diseases. Papers published by the journal represent important advances of significance to specialists within the fields of primary care and respiratory medicine. We are particularly interested in receiving papers in relation to the following aspects of respiratory medicine, respiratory-related allergic diseases and tobacco control:
epidemiology
prevention
clinical care
service delivery and organisation of healthcare (including implementation science)
global health.