乳腺癌在超声和临床方面的免疫组织化学亚型-文献综述。

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal of Ultrasonography Pub Date : 2022-04-27 eCollection Date: 2022-04-01 DOI:10.15557/JoU.2022.0016
Katarzyna Dobruch-Sobczak, Magdalena Gumowska, Joanna Mączewska, Agnieszka Kolasińska-Ćwikła, Paweł Guzik
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引用次数: 1

摘要

乳腺癌在临床和放射学表现以及对治疗的反应上都是一种异质性疾病。这主要是由于组织学类型的多态性以及个体乳腺癌类型的多样化分子谱。随着免疫组织化学研究的引入,对乳腺癌生物学的认识取得了进展。在此基础上,区分出4种主要的乳腺癌亚型:管腔A型、管腔B型、HER2阳性(人表皮生长因子受体-2阳性)和三阴性癌。将肿瘤分类为适当的亚型可以优化治疗(手术或术前化疗)。在这项研究中,作者介绍了超声检查中乳腺癌亚型的不同模式及其治疗的差异,特别强调了侵袭性乳腺癌亚型,如三阴性或HER2阳性。与腔内亚型不同,它们会造成诊断问题。基于超声图像的多因素分析,评估病变边缘、方向、形状、回声性、血管性、钙化的存在或超声弹性成像评估,可以初步区分个体亚型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Immunohistochemical Subtypes of The Breast Cancer in The Ultrasound and Clinical Aspect - Literature Review.

Immunohistochemical Subtypes of The Breast Cancer in The Ultrasound and Clinical Aspect - Literature Review.

Immunohistochemical Subtypes of The Breast Cancer in The Ultrasound and Clinical Aspect - Literature Review.

Immunohistochemical Subtypes of The Breast Cancer in The Ultrasound and Clinical Aspect - Literature Review.

Breast cancer is a heterogeneous disease both in its clinical and radiological manifestations and response to treatment. This is largely due to the polymorphism of the histological types as well as diversified molecular profiles of individual breast cancer types. Progress in the understanding of the biology of breast cancer was made with the introduction of immunohistochemical research into the common practice. On this basis, four main breast cancer subtypes were distinguished: luminal A, luminal B, HER2 positive (human epidermal growth factor receptor-2 positive), and triple negative cancer. The classification of a tumour to an appropriate subtype allows for the optimisation of treatment (surgery or pre-operative chemotherapy). In this study, the authors present different patterns of breast cancer subtypes in ultrasound examination and differences in their treatment, with particular emphasis on aggressive breast cancer subtypes, such as triple negative or HER2 positive. They can, unlike the luminal subtypes, create diagnostic problems. Based on multifactorial analysis of the ultrasound image, with the assessment of lesion margins, orientation, shape, echogenicity, vascularity, the presence of calcifications or assessment by sonoelastography, it is possible to initially differentiate individual subtypes.

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来源期刊
Journal of Ultrasonography
Journal of Ultrasonography RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.30
自引率
0.00%
发文量
58
审稿时长
20 weeks
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