利用深度学习和迁移学习预测神经外科住院病人的出院规划结果。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2025-02-01 Epub Date: 2022-12-02 DOI:10.1080/02688697.2022.2151565
Lydia Lam, Antoinette Lam, Stephen Bacchi, Amal Abou-Hamden
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引用次数: 0

摘要

简介深度学习可能有助于预测神经外科住院病人的预后。本研究旨在研究深度学习和迁移学习在预测包括出院时间和出院目的地在内的几种住院结果方面的应用:从现有数据库中收集了 15 个月内连续神经外科住院患者的数据。预处理后,将人工神经网络应用于入院记录和查房记录,以预测四种住院结果。先在训练数据集上建立模型,然后在暂缓测试数据集和验证数据集上进行测试:研究共纳入了 1341 名住院患者。使用迁移学习和人工神经网络,在推导数据集和验证数据集上,利用每日查房记录预测未来 48 小时内的出院情况,接收者运算曲线下面积(AUC)分别为 0.81 和 0.80。与此结果相比,使用不带迁移学习的人工神经网络预测相同结果时的 AUC 分别为 0.71 和 0.68。当将带迁移学习的人工神经网络应用于其他结果时,在验证数据集上,预测未来 7 天内出院、出院后存活率和出院回家率的 AUC 分别为 0.72、0.93 和 0.83:深度学习可以从自由文本医疗数据中预测神经外科住院病人的预后。利用查房记录进行重复预测,可以在这些预测中使用整个入院过程中获得的信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neurosurgery inpatient outcome prediction for discharge planning with deep learning and transfer learning.

Introduction: Deep learning may be able to assist with the prediction of neurosurgical inpatient outcomes. The aims of this study were to investigate deep learning and transfer learning in the prediction of several inpatient outcomes including timing of discharge and discharge destination.

Method: Data were collected on consecutive neurosurgical admissions from existing databases over a 15-month period. Following pre-processing artificial neural networks were applied to admission notes and ward round notes to predict four inpatient outcomes. Models were developed on the training dataset, before being tested on a hold-out test dataset and a validation dataset.

Results: 1341 individual admissions were included in the study. Using transfer learning and an artificial neural network an area under the receiver operator curve (AUC) of 0.81 and 0.80 on the derivation and validation datasets was able to be achieved for the prediction of discharge within the next 48 hours using daily ward round notes. This result is in comparison to an AUC of 0.71 and 0.68 using an artificial neural network without transfer learning for the same outcome. When the artificial neural network with transfer learning was applied to the other outcomes AUC of 0.72, 0.93 and 0.83 was achieved on the validation datasets for predicting discharge within the next 7 days, survival to discharge and discharge to home as a destination.

Conclusions: Deep learning may predict inpatient neurosurgery outcomes from free-text medical data. Recurrent predictions with ward round notes enable the use of information obtained throughout hospital admissions in these estimates.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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