利托普利用于头外型:有效和安全吗?

Obstetrics & gynecology science Pub Date : 2022-09-01 Epub Date: 2022-07-29 DOI:10.5468/ogs.22106
Sin Ae Kim, Eun-Hwan Cha, Kyoung-Chul Chun, Young Ah Kim, Jae-Whoan Koh, Jung Yeol Han, Jong Hee Hwang
{"title":"利托普利用于头外型:有效和安全吗?","authors":"Sin Ae Kim,&nbsp;Eun-Hwan Cha,&nbsp;Kyoung-Chul Chun,&nbsp;Young Ah Kim,&nbsp;Jae-Whoan Koh,&nbsp;Jung Yeol Han,&nbsp;Jong Hee Hwang","doi":"10.5468/ogs.22106","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The external cephalic version (ECV) has been shown to lower the likelihood of cesarean section requirements among pregnant women with breech presentations. In the current study, we investigated the effectiveness and safety of ritodrine as a tocolytic for ECV.</p><p><strong>Methods: </strong>A total of 407 pregnant women with breech presentations, who had no contraindications for ECV, were enrolled in this study. Multivariable logistic regression analyses were used to assess the impact of ritodrine use on the safety and efficacy of ECV.</p><p><strong>Results: </strong>The overall success rate was 67.6%, and ritodrine use was associated with significantly higher odds of successful ECV after adjusting for confounders. Moreover, using ritodrine did not increase the risk of adverse effects, including temporary changes in fetal heart rate, need for elective or emergency cesarean section due to fetal distress during ECV, low Apgar scores, and perinatal mortality.</p><p><strong>Conclusion: </strong>Our results suggest that using ritodrine as a tocolytic during ECV may increase the likelihood of ECV success and may not increase adverse perinatal outcomes.</p>","PeriodicalId":520726,"journal":{"name":"Obstetrics & gynecology science","volume":" ","pages":"420-429"},"PeriodicalIF":0.0000,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ad/fc/ogs-22106.PMC9483666.pdf","citationCount":"1","resultStr":"{\"title\":\"Ritodrine in external cephalic version: is it effective and safe?\",\"authors\":\"Sin Ae Kim,&nbsp;Eun-Hwan Cha,&nbsp;Kyoung-Chul Chun,&nbsp;Young Ah Kim,&nbsp;Jae-Whoan Koh,&nbsp;Jung Yeol Han,&nbsp;Jong Hee Hwang\",\"doi\":\"10.5468/ogs.22106\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>The external cephalic version (ECV) has been shown to lower the likelihood of cesarean section requirements among pregnant women with breech presentations. In the current study, we investigated the effectiveness and safety of ritodrine as a tocolytic for ECV.</p><p><strong>Methods: </strong>A total of 407 pregnant women with breech presentations, who had no contraindications for ECV, were enrolled in this study. Multivariable logistic regression analyses were used to assess the impact of ritodrine use on the safety and efficacy of ECV.</p><p><strong>Results: </strong>The overall success rate was 67.6%, and ritodrine use was associated with significantly higher odds of successful ECV after adjusting for confounders. Moreover, using ritodrine did not increase the risk of adverse effects, including temporary changes in fetal heart rate, need for elective or emergency cesarean section due to fetal distress during ECV, low Apgar scores, and perinatal mortality.</p><p><strong>Conclusion: </strong>Our results suggest that using ritodrine as a tocolytic during ECV may increase the likelihood of ECV success and may not increase adverse perinatal outcomes.</p>\",\"PeriodicalId\":520726,\"journal\":{\"name\":\"Obstetrics & gynecology science\",\"volume\":\" \",\"pages\":\"420-429\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ad/fc/ogs-22106.PMC9483666.pdf\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Obstetrics & gynecology science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5468/ogs.22106\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/7/29 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Obstetrics & gynecology science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5468/ogs.22106","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/7/29 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

目的:颅外切口(ECV)已被证明可以降低有臀位表现的孕妇剖宫产的可能性。在目前的研究中,我们研究了利托卡因作为ECV的抗早产药物的有效性和安全性。方法:共有407名无ECV禁忌症的孕妇参加了这项研究。采用多变量logistic回归分析评估利托君使用对ECV安全性和有效性的影响。结果:总成功率为67.6%,在调整混杂因素后,利托君的使用与ECV成功的几率显著增加相关。此外,使用利托宁不会增加不良反应的风险,包括胎儿心率的暂时变化、由于ECV期间胎儿窘迫而需要选择性或紧急剖宫产、低Apgar评分和围产期死亡率。结论:我们的研究结果表明,在ECV期间使用利托卡因作为抗早产药物可能会增加ECV成功的可能性,而不会增加不良的围产期结局。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Ritodrine in external cephalic version: is it effective and safe?

Ritodrine in external cephalic version: is it effective and safe?

Objective: The external cephalic version (ECV) has been shown to lower the likelihood of cesarean section requirements among pregnant women with breech presentations. In the current study, we investigated the effectiveness and safety of ritodrine as a tocolytic for ECV.

Methods: A total of 407 pregnant women with breech presentations, who had no contraindications for ECV, were enrolled in this study. Multivariable logistic regression analyses were used to assess the impact of ritodrine use on the safety and efficacy of ECV.

Results: The overall success rate was 67.6%, and ritodrine use was associated with significantly higher odds of successful ECV after adjusting for confounders. Moreover, using ritodrine did not increase the risk of adverse effects, including temporary changes in fetal heart rate, need for elective or emergency cesarean section due to fetal distress during ECV, low Apgar scores, and perinatal mortality.

Conclusion: Our results suggest that using ritodrine as a tocolytic during ECV may increase the likelihood of ECV success and may not increase adverse perinatal outcomes.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信