使用氟化物预防儿童和青少年的牙齿侵蚀和腐蚀性牙齿磨损。

A Lussi, M A R Buzalaf, D Duangthip, V Anttonen, C Ganss, S H João-Souza, T Baumann, T S Carvalho
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引用次数: 74

摘要

背景:牙蚀性磨损(ETW)的临床意义越来越大。据估计,全世界有30-50%的乳牙和20-45%的恒牙受到影响。导致ETW的最重要的营养因素之一是软饮料的过度消费,但与患者相关的因素,如反流或饮食失调,也会导致糜烂性病变。酸是否会导致侵蚀性脱矿取决于它们在实际pH值下对牙齿矿物质的饱和程度。回顾:氟化物,如钠或氟化胺,似乎对侵蚀的功效有限,主要原因是在侵蚀过程中缺少生物膜,以及酸的pH值比细菌酸低。这意味着,为了达到某种预防效果,有必要使用氟化物浓度较高的产品,这对幼小儿童来说不是一个合适的选择,或者增加使用频率。此外,氟化物与钛或锡离子结合时,发现氟化物具有良好的效果。TiF4可以形成耐酸的表面涂层,当使用Sn2+/F-配方时,Sn不仅存在于表面,而且还会被纳入牙釉质和牙本质中。这两种作用使牙齿表面更能抵抗酸脱矿。为了防止腐蚀/ETW,已经测试了不同的含氟载体,如牙膏、漱口水、凝胶和清漆。牙膏提供了一定程度的保护,特别是含Sn2+的配方,但活性成分的效果有时会被磨料的存在所抵消。结论:发现相关因素并对其进行影响是抑制牙体侵蚀磨损的主要手段。此外,有牙齿侵蚀风险的患者应始终使用额外的氟化物来源,最好含有Sn2+。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The use of fluoride for the prevention of dental erosion and erosive tooth wear in children and adolescents.

Background: Erosive tooth wear (ETW) has gained increasing clinical relevance. It is estimated that worldwide 30-50% of deciduous and 20-45% of permanent teeth are affected. One of the most important nutritional factors causing ETW is the overconsumption of soft drinks, but also patient-related factors like reflux or eating disorders can lead to erosive lesions. Whether acids lead to erosive demineralisation depends on their degree of saturation with respect to tooth mineral at their actual pH.

Review: Fluoride compounds like sodium or amine fluoride seem to be of limited efficacy against erosion, the main reason for this is the missing biofilm in the erosive process as well as the lower pH of the acids compared to bacterial acids. This means that to achieve some kind of preventive effect it would be necessary to use products with higher fluoride concentration, which is not an appropriate option for small children, and/or to increase the frequency of application. In addition, the fluoride compound plays a role as promising effects were found when fluoride is combined with titanium or stannous ions. TiF4 can cause acid-resistant surface coatings and when Sn2+/F- formulations are applied, Sn is not only found on the surface but is also incorporated into enamel and dentine. Both effects make the tooth surface more resistant against acid demineralisation. Different fluoride-containing vehicles have been tested to prevent erosion/ETW, such as toothpastes, rinses, gels and varnishes. Toothpastes offer some degree of protection, especially Sn2+-containing formulations, but effects of the active ingredients are sometimes counteracted by the presence of abrasives.

Conclusion: Detecting associated factors and influencing them is the main instrument in arresting erosive tooth wear. Additionally, patients at risk for dental erosion should always use an additional fluoride source preferably containing Sn2+.

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