饲粮中二氧化钛纳米颗粒对模式生物黑粉蚧代谢和生化参数的生态毒理学影响

IF 1.2 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES
Serkan Sugeçti, Benay Tunçsoy, Ender Büyükgüzel, Pınar Özalp, Kemal Büyükgüzel
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引用次数: 4

摘要

纳米粒子(NPs)现在被用于许多工业活动,如采矿、油漆和玻璃工业。NPs的频繁工业使用会造成环境污染,并可能导致原生生物的细胞和氧化损伤。本研究以大黄蜂幼虫为模型昆虫,研究了二氧化钛纳米颗粒(TiO2 NPs)的毒性作用。研究了不同浓度TiO2 NPs(5、50、250和1250 μg/mL)对黄颡鱼幼鱼血淋巴中丙氨酸转移酶、天冬氨酸转移酶、乳酸脱氢酶、非酶抗氧化剂及生化指标的影响。TiO2 NPs在大黄蜂幼虫血淋巴中引起浓度依赖性细胞损伤,并增加非酶抗氧化剂尿酸和胆红素的水平。当TiO2 NPs浓度达到最高(1250 μg/mL)时,血淋巴总蛋白显著降低。TiO2 NPs浓度最高(1250 μg/mL)时,尿素水平升高,而葡萄糖含量不受影响。这些结果表明TiO2 NPs对大黄蜂幼虫具有浓度依赖性的毒性作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ecotoxicological effects of dietary titanium dioxide nanoparticles on metabolic and biochemical parameters of model organism Galleria mellonella (Lepidoptera: Pyralidae).

Nanoparticles (NPs) are now being used in many industrial activities, such as mining, paint and glass industries. The frequent industrial use of NPs contributes to environmental pollution and may cause cellular and oxidative damage in native organisms. In this study, the toxic effects of titanium dioxide nanoparticles (TiO2 NPs) were investigated using Galleria mellonella larvae as a model insect species. Alterations in cell damage indicators, such as alanine transferase, aspartate transferase, lactate dehydrogenase, non-enzymatic antioxidants and biochemical parameters, were determined in the hemolymph of G. mellonella larvae exposed to TiO2 NPs at different concentrations (5, 50, 250 and 1250 μg/mL) in their diets. TiO2 NPs caused concentration-dependent cellular damage in the hemolymph of G. mellonella larvae and increased the levels of the non-enzymatic antioxidants uric acid and bilirubin. In addition, total protein in hemolymph significantly decreased at the highest concentration (1250 μg/mL) of TiO2 NPs. Level of the urea increased at the highest concentration (1250 μg/mL) of TiO2 NPs, whereas the amount of glucose was not affected. These findings demonstrated that TiO2 NPs caused concentration-dependent toxic effects on G. mellonella larvae.

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CiteScore
4.60
自引率
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发文量
10
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