{"title":"COVID-19大流行期间医护人员SARS-CoV-2再阳性PCR分析","authors":"Masoud Alebouyeh, Pooya Aavani, Nareen Arif Abdulrahman, Azad Abduljabar Haleem, Abdollah Karimi, Shahnaz Armin, Fatemeh Fallah, Arezu Amirali, Saeed Sadr, Ghazaleh Ghandchi, Nafiseh Abdollahi, Roxana Mansour Ghanaie, Sedigheh Rafiei Tabatabaei, Seyed Alireza Fahimzad, Raheleh Razmara, Khalid J Alzahrani, Ghamartaj Khanbabaee, Soheila Sadat Vaghefi, Farid Imanzadeh, Peyman Eshghi, Leila Azimi","doi":"10.14715/cmb/2021.67.5.19","DOIUrl":null,"url":null,"abstract":"<p><p>Reinfection rate with SARS-CoV-2 and degree of protection by the induced antibody after the first episode of the infection is not well known, so it makes a big dilemma for health care personnel (HCP) who work in the front line of combating SARS-CoV-2. In this study, we investigated the frequency of SARS-CoV-2 redetection among HCP after the initial onset of the infection in a children's hospital during one year. Out of 131 seropositive HCP, 13.7% of them were symptomatic and PCR positive during 74-360 days after first sampling. Analysis of demographic data of seropositive HCP showed a correlation between a higher number of family members, higher body mass index, and the existence of underlying diseases with SARS-CoV-2 redetection. In conclusion, reinfection is one of the important problems in the SARS-CoV-2 pandemic. Research on this topic can help us to find answers to questions for estimating the duration of human protection with produced immunity after the infection or vaccination.</p>","PeriodicalId":520584,"journal":{"name":"Cellular and molecular biology (Noisy-le-Grand, France)","volume":" ","pages":"138-143"},"PeriodicalIF":0.0000,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Re-positive PCR of SARS-CoV-2 in health care persons during COVID-19 pandemic.\",\"authors\":\"Masoud Alebouyeh, Pooya Aavani, Nareen Arif Abdulrahman, Azad Abduljabar Haleem, Abdollah Karimi, Shahnaz Armin, Fatemeh Fallah, Arezu Amirali, Saeed Sadr, Ghazaleh Ghandchi, Nafiseh Abdollahi, Roxana Mansour Ghanaie, Sedigheh Rafiei Tabatabaei, Seyed Alireza Fahimzad, Raheleh Razmara, Khalid J Alzahrani, Ghamartaj Khanbabaee, Soheila Sadat Vaghefi, Farid Imanzadeh, Peyman Eshghi, Leila Azimi\",\"doi\":\"10.14715/cmb/2021.67.5.19\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Reinfection rate with SARS-CoV-2 and degree of protection by the induced antibody after the first episode of the infection is not well known, so it makes a big dilemma for health care personnel (HCP) who work in the front line of combating SARS-CoV-2. In this study, we investigated the frequency of SARS-CoV-2 redetection among HCP after the initial onset of the infection in a children's hospital during one year. Out of 131 seropositive HCP, 13.7% of them were symptomatic and PCR positive during 74-360 days after first sampling. Analysis of demographic data of seropositive HCP showed a correlation between a higher number of family members, higher body mass index, and the existence of underlying diseases with SARS-CoV-2 redetection. In conclusion, reinfection is one of the important problems in the SARS-CoV-2 pandemic. Research on this topic can help us to find answers to questions for estimating the duration of human protection with produced immunity after the infection or vaccination.</p>\",\"PeriodicalId\":520584,\"journal\":{\"name\":\"Cellular and molecular biology (Noisy-le-Grand, France)\",\"volume\":\" \",\"pages\":\"138-143\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-02-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cellular and molecular biology (Noisy-le-Grand, France)\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.14715/cmb/2021.67.5.19\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cellular and molecular biology (Noisy-le-Grand, France)","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.14715/cmb/2021.67.5.19","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Re-positive PCR of SARS-CoV-2 in health care persons during COVID-19 pandemic.
Reinfection rate with SARS-CoV-2 and degree of protection by the induced antibody after the first episode of the infection is not well known, so it makes a big dilemma for health care personnel (HCP) who work in the front line of combating SARS-CoV-2. In this study, we investigated the frequency of SARS-CoV-2 redetection among HCP after the initial onset of the infection in a children's hospital during one year. Out of 131 seropositive HCP, 13.7% of them were symptomatic and PCR positive during 74-360 days after first sampling. Analysis of demographic data of seropositive HCP showed a correlation between a higher number of family members, higher body mass index, and the existence of underlying diseases with SARS-CoV-2 redetection. In conclusion, reinfection is one of the important problems in the SARS-CoV-2 pandemic. Research on this topic can help us to find answers to questions for estimating the duration of human protection with produced immunity after the infection or vaccination.
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