伪装在碱血症背后的糖尿病酮症酸中毒是一种未确诊或遗漏的糖尿病酮症酸中毒变体。

IF 1
Vishnu Priyaa Rajasegaran, Preethi Tamilarasan, Thambiprabagarane Kalaimani
{"title":"伪装在碱血症背后的糖尿病酮症酸中毒是一种未确诊或遗漏的糖尿病酮症酸中毒变体。","authors":"Vishnu Priyaa Rajasegaran, Preethi Tamilarasan, Thambiprabagarane Kalaimani","doi":"10.1515/jpem-2022-0115","DOIUrl":null,"url":null,"abstract":"Abstract Objectives Diabetic ketoacidosis is a common emergency in type 1 diabetes mellitus patients. But rarely, they may present with alkalemia instead of acidosis. Diabetic ketoalkalosis which has been reported in adults can also be present in children with type 1 DM. The usual factors causing alkalemia were not found in our patients. This entity may manifest in both newly diagnosed and treated patients. Case presentation The first patient, an 8 year male presented with features of DKA, was diagnosed for the first time as type 1 DM, but was found to have alkalemia. The second patient, a 7 year female was a known case of Type 1 DM on insulin, who presented with dehydration and alkalemia. Both were treated with hydration and insulin and made complete recovery. Conclusions A normal or alkalotic pH does not essentially eliminate DKA and needs to be evaluated further to identify the underlying acid–base disturbance.","PeriodicalId":520684,"journal":{"name":"Journal of pediatric endocrinology & metabolism : JPEM","volume":" ","pages":"1316-1318"},"PeriodicalIF":1.0000,"publicationDate":"2022-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diabetic ketoacidosis masquerading behind alkalemia an undiagnosed or missed variant of diabetic ketoacidosis.\",\"authors\":\"Vishnu Priyaa Rajasegaran, Preethi Tamilarasan, Thambiprabagarane Kalaimani\",\"doi\":\"10.1515/jpem-2022-0115\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract Objectives Diabetic ketoacidosis is a common emergency in type 1 diabetes mellitus patients. But rarely, they may present with alkalemia instead of acidosis. Diabetic ketoalkalosis which has been reported in adults can also be present in children with type 1 DM. The usual factors causing alkalemia were not found in our patients. This entity may manifest in both newly diagnosed and treated patients. Case presentation The first patient, an 8 year male presented with features of DKA, was diagnosed for the first time as type 1 DM, but was found to have alkalemia. The second patient, a 7 year female was a known case of Type 1 DM on insulin, who presented with dehydration and alkalemia. Both were treated with hydration and insulin and made complete recovery. Conclusions A normal or alkalotic pH does not essentially eliminate DKA and needs to be evaluated further to identify the underlying acid–base disturbance.\",\"PeriodicalId\":520684,\"journal\":{\"name\":\"Journal of pediatric endocrinology & metabolism : JPEM\",\"volume\":\" \",\"pages\":\"1316-1318\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2022-07-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of pediatric endocrinology & metabolism : JPEM\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1515/jpem-2022-0115\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/10/26 0:00:00\",\"PubModel\":\"Print\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of pediatric endocrinology & metabolism : JPEM","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1515/jpem-2022-0115","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/10/26 0:00:00","PubModel":"Print","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

目的:糖尿病酮症酸中毒是1型糖尿病患者常见的急症。但很少,他们可能表现为碱血症而不是酸中毒。在成人中报道的糖尿病酮症碱中毒也可出现在1型糖尿病儿童中。在我们的患者中未发现引起碱血症的常见因素。这种实体可以在新诊断和治疗的患者中表现出来。病例介绍:第一例患者,一名8岁男性,表现为DKA特征,首次诊断为1型糖尿病,但发现有碱血症。第二例患者为一名7岁女性,已知为胰岛素治疗的1型糖尿病,表现为脱水和碱血症。两例患者均经水合及胰岛素治疗,均完全康复。结论:正常或碱碱性的pH值并不能完全消除DKA,需要进一步评估以确定潜在的酸碱紊乱。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diabetic ketoacidosis masquerading behind alkalemia an undiagnosed or missed variant of diabetic ketoacidosis.
Abstract Objectives Diabetic ketoacidosis is a common emergency in type 1 diabetes mellitus patients. But rarely, they may present with alkalemia instead of acidosis. Diabetic ketoalkalosis which has been reported in adults can also be present in children with type 1 DM. The usual factors causing alkalemia were not found in our patients. This entity may manifest in both newly diagnosed and treated patients. Case presentation The first patient, an 8 year male presented with features of DKA, was diagnosed for the first time as type 1 DM, but was found to have alkalemia. The second patient, a 7 year female was a known case of Type 1 DM on insulin, who presented with dehydration and alkalemia. Both were treated with hydration and insulin and made complete recovery. Conclusions A normal or alkalotic pH does not essentially eliminate DKA and needs to be evaluated further to identify the underlying acid–base disturbance.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信