{"title":"补充亚麻籽油对超重糖尿病前期成人机体成分和炎症指标的影响。","authors":"Elham Shareghfarid, Azadeh Nadjarzadeh, Neda Heidarzadeh-Esfahani, Yasaman Azamian, Salimeh Hajiahmadi","doi":"10.1177/11786388221090083","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Flaxseed has rich content of alpha linolenic acid for preventing pro inflammatory process. The aim of present study is exploring the effect of flaxseed oil supplementation on inflammatory biomarkers and body composition in overweight adults with pre-diabetes.</p><p><strong>Material and methods: </strong>this double-blind randomized clinical trial conducted with 80 overweight pre-diabetic patients in 2 clusters (flaxseed oil group (2000-mg daily) and control group) across a 14-week period. Anthropometric indices, body composition and inflammatory indices were measured between 2 groups before and after the treatment.</p><p><strong>Result: </strong>this study found a significant decrease in visceral fat level in the intervention group (<i>P</i> = .009) and control group (<i>P</i> = .004) at the end of the survey. However, the mean change of it (<i>P</i> = .06) was not significant. Also, this study showed that percentage of body fat (<i>P</i> = .31) and its mean change (<i>P</i> = .6) did not have significantly different between the 2 groups at the 14th week. The skeletal muscle% had a significant rise in the intervention group (<i>P</i> = .005) and control group (<i>P</i> = .003) by the end of 14th week. However, the mean change of it (<i>P</i> = .19) was not significant between the 2 groups. In addition, there was no significant change in the fasting blood glucose (<i>P</i> = . 7), C reactive protein (<i>P</i> = .12) and TNF-α (<i>P</i> = .22) between the 2 groups at the end of study.</p><p><strong>Conclusion: </strong>It showed that flaxseed oil supplementation cannot improve body composition and inflammation.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ce/d5/10.1177_11786388221090083.PMC9253991.pdf","citationCount":"3","resultStr":"{\"title\":\"The Effect of Flaxseed Oil Supplementation on Body Composition and Inflammation Indices in Overweight Adults With Pre-Diabetes.\",\"authors\":\"Elham Shareghfarid, Azadeh Nadjarzadeh, Neda Heidarzadeh-Esfahani, Yasaman Azamian, Salimeh Hajiahmadi\",\"doi\":\"10.1177/11786388221090083\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Flaxseed has rich content of alpha linolenic acid for preventing pro inflammatory process. The aim of present study is exploring the effect of flaxseed oil supplementation on inflammatory biomarkers and body composition in overweight adults with pre-diabetes.</p><p><strong>Material and methods: </strong>this double-blind randomized clinical trial conducted with 80 overweight pre-diabetic patients in 2 clusters (flaxseed oil group (2000-mg daily) and control group) across a 14-week period. Anthropometric indices, body composition and inflammatory indices were measured between 2 groups before and after the treatment.</p><p><strong>Result: </strong>this study found a significant decrease in visceral fat level in the intervention group (<i>P</i> = .009) and control group (<i>P</i> = .004) at the end of the survey. However, the mean change of it (<i>P</i> = .06) was not significant. Also, this study showed that percentage of body fat (<i>P</i> = .31) and its mean change (<i>P</i> = .6) did not have significantly different between the 2 groups at the 14th week. The skeletal muscle% had a significant rise in the intervention group (<i>P</i> = .005) and control group (<i>P</i> = .003) by the end of 14th week. However, the mean change of it (<i>P</i> = .19) was not significant between the 2 groups. In addition, there was no significant change in the fasting blood glucose (<i>P</i> = . 7), C reactive protein (<i>P</i> = .12) and TNF-α (<i>P</i> = .22) between the 2 groups at the end of study.</p><p><strong>Conclusion: </strong>It showed that flaxseed oil supplementation cannot improve body composition and inflammation.</p>\",\"PeriodicalId\":19396,\"journal\":{\"name\":\"Nutrition and Metabolic Insights\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2022-06-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ce/d5/10.1177_11786388221090083.PMC9253991.pdf\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nutrition and Metabolic Insights\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/11786388221090083\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"NUTRITION & DIETETICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nutrition and Metabolic Insights","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/11786388221090083","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
The Effect of Flaxseed Oil Supplementation on Body Composition and Inflammation Indices in Overweight Adults With Pre-Diabetes.
Background: Flaxseed has rich content of alpha linolenic acid for preventing pro inflammatory process. The aim of present study is exploring the effect of flaxseed oil supplementation on inflammatory biomarkers and body composition in overweight adults with pre-diabetes.
Material and methods: this double-blind randomized clinical trial conducted with 80 overweight pre-diabetic patients in 2 clusters (flaxseed oil group (2000-mg daily) and control group) across a 14-week period. Anthropometric indices, body composition and inflammatory indices were measured between 2 groups before and after the treatment.
Result: this study found a significant decrease in visceral fat level in the intervention group (P = .009) and control group (P = .004) at the end of the survey. However, the mean change of it (P = .06) was not significant. Also, this study showed that percentage of body fat (P = .31) and its mean change (P = .6) did not have significantly different between the 2 groups at the 14th week. The skeletal muscle% had a significant rise in the intervention group (P = .005) and control group (P = .003) by the end of 14th week. However, the mean change of it (P = .19) was not significant between the 2 groups. In addition, there was no significant change in the fasting blood glucose (P = . 7), C reactive protein (P = .12) and TNF-α (P = .22) between the 2 groups at the end of study.
Conclusion: It showed that flaxseed oil supplementation cannot improve body composition and inflammation.
期刊介绍：
Nutrition and Metabolic Insights is a peer-reviewed, open-access online journal focusing on all aspects of nutrition and metabolism. This encompasses nutrition, including the biochemistry of metabolism, exercise and associated physical processes and also includes clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes. It includes research at the molecular, cellular and organismal levels. This journal welcomes new manuscripts for peer review on the following topics: Nutrition, including the biochemistry of metabolism, Exercise and associated physical processes, Clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes, Research at the molecular, cellular and organismal levels, Other areas of interest include gene-nutrient interactions, the effects of hormones, models of metabolic function, macronutrient interactions, outcomes of changes in diet, and pathophysiology.
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