民间药物:西番莲的抗氧化活性。

IF 1.8 Q3 PHARMACOLOGY & PHARMACY
Helan Soundra Rani Michael, Nazneen Bobby Mohammed, Subramaniam Ponnusamy, Wesely Edward Gnanaraj
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引用次数: 1

摘要

目的:西番莲(Passiflora incarnata L.),通常被称为民间药物,用于广泛的治疗目的,其中之一是抗氧化效力。通过1,1-二苯基-2-苦味酰肼(DPPH)猝灭试验、2,2-氮基-双-(3-乙基苯并噻唑啉-6-磺酸)阳离子脱色试验、超氧化物和过氧化氢自由基清除试验,对红花叶乙醇提取物的总酚类、类黄酮、生物碱和单宁含量进行了植物化学分析,并对其抗氧化性能进行了研究。材料与方法:对其色、香、形、味等感官特征及干燥范围、纤维含量等其他性状进行初步分析。总酚含量、总单宁含量、总生物碱含量、总黄酮等分析参数对不同浓度乙醇提取物的抑制率均达到IC50 (μg/mL),具有多种抗自由基清除活性(DPPH、ABTS、超氧化物和H2O2清除试验)。结果:红枣叶中酚类物质含量为2.48 mg没食子酸当量/g,总黄酮含量为2.1 mg /g,具有较强的自由基清除能力。结论:红皮提取物具有较高的抗氧化活性,可能与红皮提取物中黄酮类和酚类物质含量较高有关。研究结果表明,在科学研究和制药工业中,螺旋藻是一种名副其实的抗氧化药物生物勘探来源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A Folk Medicine: <i>Passiflora incarnata</i> L. Phytochemical Profile with Antioxidant Potency.

A Folk Medicine: Passiflora incarnata L. Phytochemical Profile with Antioxidant Potency.

Objectives: Passiflora incarnata L., commonly called folk medicine declaredly used for an enormous range of therapeutic purposes, one such is antioxidant potency. The study prioritized to determine the phytochemical analysis of total phenolics, flavonoids, alkaloids, and tannins contents as well as the antioxidant properties through 1,1-diphenyl-2-picrylhydrazyl (DPPH) quenching assay, 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) cation decolorization test, superoxide, and hydrogen peroxide radical scavenging assays of ethanol extract of P. incarnata leaves.

Materials and methods: The organoleptic characteristics such as color, odor, appearance, taste, and other characters such as drying range and fiber contents were analyzed as preliminary data. Analytical parameters like total phenolic content, total tannins, total alkaloid content, and total flavonoid with multiple antiradical scavenging activity (DPPH, ABTS, superoxide and H2O2 scavenging assays) with IC50 (μg/mL) in terms of inhibition percentage with various concentrations of the ethanolic extract studied.

Results: P. incarnata possessed a high radical scavenging activity with a phenolic content of 2.48 mg gallic acid equivalent/g of extract in leaves, whereas the total flavonoid content was 2.1, respectively.

Conclusion: High antioxidant activity was noticed in P. incarnata extract, in which might be of higher levels of flavonoids and phenols. Findings in the studies revealed that P. incarnata is a veritable source for antioxidant drug bioprospecting in scientific research and pharmaceutical industries.

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来源期刊
CiteScore
3.60
自引率
5.90%
发文量
79
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