一例继发于前列腺转移的单侧突眼病例

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2025-03-01 Epub Date: 2022-08-25 DOI:10.1177/01455613221119067
Jennifer A Silver, Hamad Almhanedi, Jonathan K Lai, Alex C Tham, Oluyomi Ajise, Marc A Tewfik
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引用次数: 0

摘要

前列腺癌转移累及眼眶和/或副鼻窦是一种罕见的肿瘤表现。患者可出现眼球突出、眶周肿胀、视力模糊、鼻出血、鼻衄、嗅觉障碍等多种症状,具体取决于受累结构。影像学检查对副鼻窦肿块的鉴别诊断范围很广,可包括炎症性、先天性或肿瘤性肿块,因此需要进行活组织检查以明确诊断。组织样本通常通过内窥镜方法获得。文献中对这种病症的预后没有很好的描述,但由于该病处于晚期,且原发肿瘤通常分化较差,因此预后通常较差。治疗的目的通常是减轻疾病负担和清除肿瘤块,以达到姑息目的。我们为您介绍一例因前列腺转移而继发单侧突眼和眶周肿胀的 71 岁男性病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Case of Unilateral Proptosis Secondary to Prostatic Metastasis.

Prostate cancer metastases involving the orbit and/or paranasal sinuses represent a rare oncological presentation. Patients can have a myriad of symptoms such as proptosis, periorbital swelling, blurry vision, rhinorrhea, epistaxis, anosmia, or others depending on the structures involved. The differential diagnosis of paranasal sinus masses on imaging studies is broad and can include inflammatory, congenital, or neoplastic masses; leading to the requirement of biopsy for definitive diagnosis. Tissue sample is usually obtained via an endoscopic approach. The prognosis of such a presentation is not well described in the literature, but it is usually guarded due to the advanced stage of the disease and generally a poorly differentiated primary tumor. Treatments usually aim to reduce the burden of disease and debulk the tumor mass for palliative purposes. We present a case of a 71-year-old male presenting with unilateral proptosis and periorbital swelling secondary to prostatic metastasis.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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