胸膜卡波济肉瘤一例罕见的临床病例。

IF 4.4 Q1 PATHOLOGY
PATHOLOGICA Pub Date : 2022-10-01 DOI:10.32074/1591-951X-778
Alessandro Marando, Giuseppe Isimbaldi, Sascia Pietro Servillo, Emanuela Bonoldi
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引用次数: 0

摘要

卡波西肉瘤是一种与人类疱疹病毒-8相关的低级别间充质肿瘤。我们在此报告一位37岁的女性,因先天性肝纤维化和双侧多囊肾接受了两肾和肝脏移植,并接受了连续的免疫抑制治疗。第一次移植5年后,患者出现卡波西肉瘤的皮肤、粘膜、胸膜和淋巴结定位,未见肺部病变。由于最初的临床表现有重要的淋巴结和胸膜受累,我们怀疑诊断为淋巴增生性疾病。胸膜标本的病理检查排除了淋巴增生性肿瘤,与卡波西肉瘤一致。随后,其他部位受累被诊断为弥漫性疾病的表达。本病例的兴趣在于不寻常的临床表现,这可能导致诊断陷阱时,评估胸膜活检。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Pleural Kaposi sarcoma: an unusual clinical case.

Pleural Kaposi sarcoma: an unusual clinical case.

Kaposi sarcoma is a low-grade mesenchymal tumor associated with human herpesvirus-8. Here we describe the case of a 37-year old woman, who underwent to kidney and liver transplant for congenital hepatic fibrosis and bilateral polycystic kidney, with successive immunosuppressive therapy. After 5 years from first transplant, she developed cutaneous, mucosal, pleural and nodal localizations of Kaposi sarcoma, without lung lesions. Because of an initial clinical presentation with an important nodal and pleural involvement, a diagnosis of a lymphoproliferative disease was suspected. Pathological examination of the pleural sample allowed to exclude lymphoproliferative neoplasia and was consistent with Kaposi sarcoma. Subsequently involvement of other sites was diagnosed as expression of diffuse disease. The interest of this case lays in the unusual clinical presentation which can lead to diagnostic pitfalls when evaluating pleural biopsies.

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来源期刊
PATHOLOGICA
PATHOLOGICA PATHOLOGY-
CiteScore
5.90
自引率
5.70%
发文量
108
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