Kenneth A Michelson, Finn L E McGarghan, Emma E Patterson, Margaret E Samuels-Kalow, Mark L Waltzman, Kimberly F Greco
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Complications were compared between by delayed diagnosis status.</p><p><strong>Results: </strong>Among 14 972 children, delayed diagnosis occurred in 1.1% (range 0.3% for sepsis to 2.6% for ovarian torsion). Hispanic (matched OR 2.71, 95% CI 1.69 to 4.35) and non-Hispanic black (OR 2.40, 95% CI 1.21 to 4.79) race/ethnicity were associated with delayed diagnosis, whereas Asian and other race/ethnicity were not. Public (OR 2.21, 95% CI 1.42 to 3.44) and other (OR 2.43, 95% CI 1.50 to 3.93) insurance were also associated with delay. Non-English language was associated with delay (OR 1.65, 95% CI 1.02 to 2.69). Abnormal vital signs were associated with a lower likelihood of delay (OR 0.15, 95% CI 0.09 to 0.25). In an adjusted model, Hispanic race/ethnicity, other insurance, abnormal vital signs and complex chronic conditions (CCCs) were associated with delay. The odds of a complication were 2.5-fold (95% CI 1.6 to 3.8) higher among patients with a delay.</p><p><strong>Conclusion: </strong>Delayed diagnosis was uncommon across 13 regional EDs but was more likely among children with Hispanic ethnicity, CCCs or normal vital signs. Delays were associated with a higher risk of complications.</p>","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":" ","pages":"293-300"},"PeriodicalIF":8.3000,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Delayed diagnosis of serious paediatric conditions in 13 regional emergency departments.\",\"authors\":\"Kenneth A Michelson, Finn L E McGarghan, Emma E Patterson, Margaret E Samuels-Kalow, Mark L Waltzman, Kimberly F Greco\",\"doi\":\"10.1136/bmjqs-2022-015314\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To evaluate rates, risk factors and outcomes of delayed diagnosis of seven serious paediatric conditions.</p><p><strong>Methods: </strong>This was a retrospective, cross-sectional study of children under 21 years old visiting 13 community and tertiary emergency departments (EDs) with appendicitis, bacterial meningitis, intussusception, mastoiditis, ovarian torsion, sepsis or testicular torsion. Delayed diagnosis was defined as having a previous ED encounter within 1 week in which the condition was present per case review. Patients with delayed diagnosis were each matched to four control patients without delay by condition, facility and age. Conditional logistic regression models evaluated risk factors of delay. Complications were compared between by delayed diagnosis status.</p><p><strong>Results: </strong>Among 14 972 children, delayed diagnosis occurred in 1.1% (range 0.3% for sepsis to 2.6% for ovarian torsion). Hispanic (matched OR 2.71, 95% CI 1.69 to 4.35) and non-Hispanic black (OR 2.40, 95% CI 1.21 to 4.79) race/ethnicity were associated with delayed diagnosis, whereas Asian and other race/ethnicity were not. Public (OR 2.21, 95% CI 1.42 to 3.44) and other (OR 2.43, 95% CI 1.50 to 3.93) insurance were also associated with delay. Non-English language was associated with delay (OR 1.65, 95% CI 1.02 to 2.69). Abnormal vital signs were associated with a lower likelihood of delay (OR 0.15, 95% CI 0.09 to 0.25). In an adjusted model, Hispanic race/ethnicity, other insurance, abnormal vital signs and complex chronic conditions (CCCs) were associated with delay. The odds of a complication were 2.5-fold (95% CI 1.6 to 3.8) higher among patients with a delay.</p><p><strong>Conclusion: </strong>Delayed diagnosis was uncommon across 13 regional EDs but was more likely among children with Hispanic ethnicity, CCCs or normal vital signs. 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引用次数: 0
摘要
目的:评估七种严重儿科疾病的延迟诊断率、风险因素和结果:评估七种严重儿科疾病的延误诊断率、风险因素和结果:这是一项回顾性横断面研究,研究对象是因阑尾炎、细菌性脑膜炎、肠套叠、乳突炎、卵巢扭转、败血症或睾丸扭转到 13 个社区和三级急诊科(ED)就诊的 21 岁以下儿童。延迟诊断的定义是:在 1 周内曾在急诊科就诊,且每次病例回顾中均出现过该病症。根据病情、设施和年龄,将每名延迟诊断患者与四名无延迟诊断的对照组患者进行配对。条件逻辑回归模型评估了延误的风险因素。并将并发症与延迟诊断情况进行比较:在 14 972 名儿童中,有 1.1%(范围从败血症的 0.3% 到卵巢扭转的 2.6%)的儿童被延误诊断。西班牙裔(匹配 OR 2.71,95% CI 1.69 至 4.35)和非西班牙裔黑人(OR 2.40,95% CI 1.21 至 4.79)种族/人种与延迟诊断有关,而亚裔和其他种族/人种与延迟诊断无关。公共保险(OR 2.21,95% CI 1.42 至 3.44)和其他保险(OR 2.43,95% CI 1.50 至 3.93)也与延迟诊断有关。非英语语言与延误有关(OR 1.65,95% CI 1.02 至 2.69)。生命体征异常与较低的延迟可能性相关(OR 0.15,95% CI 0.09 至 0.25)。在调整模型中,西班牙裔种族/民族、其他保险、生命体征异常和复杂慢性病(CCCs)与延迟相关。延迟诊断的患者发生并发症的几率要高出 2.5 倍(95% CI 1.6 至 3.8):在13个地区的急诊室中,延误诊断的情况并不常见,但在西班牙裔、有CCC或生命体征正常的儿童中,延误诊断的可能性更大。延误与并发症风险较高有关。
Delayed diagnosis of serious paediatric conditions in 13 regional emergency departments.
Objective: To evaluate rates, risk factors and outcomes of delayed diagnosis of seven serious paediatric conditions.
Methods: This was a retrospective, cross-sectional study of children under 21 years old visiting 13 community and tertiary emergency departments (EDs) with appendicitis, bacterial meningitis, intussusception, mastoiditis, ovarian torsion, sepsis or testicular torsion. Delayed diagnosis was defined as having a previous ED encounter within 1 week in which the condition was present per case review. Patients with delayed diagnosis were each matched to four control patients without delay by condition, facility and age. Conditional logistic regression models evaluated risk factors of delay. Complications were compared between by delayed diagnosis status.
Results: Among 14 972 children, delayed diagnosis occurred in 1.1% (range 0.3% for sepsis to 2.6% for ovarian torsion). Hispanic (matched OR 2.71, 95% CI 1.69 to 4.35) and non-Hispanic black (OR 2.40, 95% CI 1.21 to 4.79) race/ethnicity were associated with delayed diagnosis, whereas Asian and other race/ethnicity were not. Public (OR 2.21, 95% CI 1.42 to 3.44) and other (OR 2.43, 95% CI 1.50 to 3.93) insurance were also associated with delay. Non-English language was associated with delay (OR 1.65, 95% CI 1.02 to 2.69). Abnormal vital signs were associated with a lower likelihood of delay (OR 0.15, 95% CI 0.09 to 0.25). In an adjusted model, Hispanic race/ethnicity, other insurance, abnormal vital signs and complex chronic conditions (CCCs) were associated with delay. The odds of a complication were 2.5-fold (95% CI 1.6 to 3.8) higher among patients with a delay.
Conclusion: Delayed diagnosis was uncommon across 13 regional EDs but was more likely among children with Hispanic ethnicity, CCCs or normal vital signs. Delays were associated with a higher risk of complications.
期刊介绍:
ACS Applied Materials & Interfaces is a leading interdisciplinary journal that brings together chemists, engineers, physicists, and biologists to explore the development and utilization of newly-discovered materials and interfacial processes for specific applications. Our journal has experienced remarkable growth since its establishment in 2009, both in terms of the number of articles published and the impact of the research showcased. We are proud to foster a truly global community, with the majority of published articles originating from outside the United States, reflecting the rapid growth of applied research worldwide.