冷却疗法对多发性硬化症患者疲劳、体力活动和生活质量的影响:一项荟萃分析。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-11-01 Epub Date: 2022-08-31 DOI:10.1097/RNJ.0000000000000388

Aylin Bilgin, Gülsah Kesik, Leyla Ozdemir

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引用次数: 1

摘要

目的:本荟萃分析探讨了冷却疗法对多发性硬化症(MS)患者的疲劳、身体活动和生活质量(QoL)的影响。方法:在6个数据库中检索2000 - 2020年间发表的文章。标准化平均差异由95%置信区间的上限和下限确定。发表偏倚通过Egger检验进行评估，该检验使用线性回归。发表偏倚采用漏斗图进行视觉检验。结果:本荟萃分析纳入了9项研究。冷却疗法的类型包括冷却服装(n = 4)、冷却装置(n = 2)、冷却室(n = 1)、预冷(n = 1)和冷水摄入(n = 1)。结果表明，冷却疗法显著减少了疲劳，增加了体力活动。冷却疗法改善了ms患者的生活质量，Egger检验显示没有明显的发表偏倚。然而，漏斗图显示研究之间有轻微的不对称性。结论和临床意义:冷却疗法对MS患者的疲劳、体力活动和生活质量有有益的影响，医疗保健专业人员可以使用冷却方法来管理MS患者的热敏症状。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Effects of Cooling Therapies on Fatigue, Physical Activity, and Quality of Life in Multiple Sclerosis: A Meta-Analysis.

Purpose: This meta-analysis examined the effects of the cooling therapies on fatigue, physical activity, and quality of life (QoL) in patients with multiple sclerosis (MS).

Methods: Articles published between 2000 and 2020 were searched in six databases. The standardized mean differences were determined by the upper and lower limits of 95% confidence intervals. Publication bias was assessed by conducting the Egger test, which uses linear regression. Publication bias was examined visually using a funnel plot.

Results: Nine studies were included in this meta-analysis. The types of cooling therapies included cooling garment ( n = 4), cooling device ( n = 2), cooling room ( n = 1), precooling ( n = 1), and cold water ingestion ( n = 1). The results indicated a significant decrease in fatigue and an increase in physical activity following cooling therapy. Cooling therapies improved the QoL of patients with MS. The Egger test indicated no significant publication bias. However, the funnel plot presented a slight asymmetry among studies.

Conclusions and clinical relevance: Cooling therapies have a beneficial effect on fatigue, physical activity, and the QoL of patients with MS. Healthcare professionals can use cooling methods to manage thermosensitive symptoms in patients with MS.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.