[老鼠、其他啮齿动物和人类的DNA修复与长寿]。

Medecine sciences : M/S Pub Date : 2022-03-01 Epub Date: 2022-03-25 DOI:10.1051/medsci/2022019

Bertrand Jordan

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引用次数: 1

摘要

不同啮齿类动物的最大寿命存在很大差异。通过单细胞(体细胞)测序测定这些物种的自发突变率和诱变剂诱导突变率表明，长寿物种(包括人类)的DNA修复效率更高，但数据过于嘈杂，无法证明长寿与DNA完整性保存之间存在很强的相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[DNA repair and longevity in mice, other rodents and men].

Large differences in maximum longevity exist between different rodent species. Determination of the spontaneous and mutagen-induced mutation rates in these species by single (somatic) cell sequencing suggests more efficient DNA repair in long-lived species (including humans), but the data is too noisy to prove a strong correlation between longevity and preservation of DNA integrity.

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Medecine sciences : M/S

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