{"title":"左乙拉西坦粘膜固定药疹,非病变皮肤早期斑贴试验阳性。","authors":"Nazli Ercan","doi":"10.1111/pai.13723","DOIUrl":null,"url":null,"abstract":"Levetiracetam (LEV) is a second-generation antiepileptic drug (AED) that\nis well tolerated, has a broad spectrum of action, low protein binding,\nand minimal hepatic metabolism. The incidence of hypersensitivity to LEV\nin children and adults is 0.6%. This is the first reported fixed drug\neruption (FDE) identified using a patch test in a pediatric case\nassociated with LEV","PeriodicalId":520742,"journal":{"name":"Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology","volume":" ","pages":"e13723"},"PeriodicalIF":4.5000,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Mucosal fixed drug eruption to levetiracetam with early positive patch test on non-lesional skin.\",\"authors\":\"Nazli Ercan\",\"doi\":\"10.1111/pai.13723\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Levetiracetam (LEV) is a second-generation antiepileptic drug (AED) that\\nis well tolerated, has a broad spectrum of action, low protein binding,\\nand minimal hepatic metabolism. The incidence of hypersensitivity to LEV\\nin children and adults is 0.6%. This is the first reported fixed drug\\neruption (FDE) identified using a patch test in a pediatric case\\nassociated with LEV\",\"PeriodicalId\":520742,\"journal\":{\"name\":\"Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology\",\"volume\":\" \",\"pages\":\"e13723\"},\"PeriodicalIF\":4.5000,\"publicationDate\":\"2022-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/pai.13723\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/pai.13723","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Mucosal fixed drug eruption to levetiracetam with early positive patch test on non-lesional skin.
Levetiracetam (LEV) is a second-generation antiepileptic drug (AED) that
is well tolerated, has a broad spectrum of action, low protein binding,
and minimal hepatic metabolism. The incidence of hypersensitivity to LEV
in children and adults is 0.6%. This is the first reported fixed drug
eruption (FDE) identified using a patch test in a pediatric case
associated with LEV