经皮质切除巨大双叶镰状脑膜瘤。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-12-01 Epub Date: 2022-02-17 DOI:10.1080/02688697.2022.2034744
Turki Elarjani, Evan Luther, Alexis A Morell, Daniel G Eichberg, Ashish H Shah, Victor M Lu, Gurvinder Kaur, Michael E Ivan, Ricardo J Komotar
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引用次数: 0

摘要

简介:镰状脑膜瘤给外科手术带来了巨大挑战,因为它们常常累及双侧镰状脑膜瘤,被大量正常脑实质所掩盖,而且位置较深,靠近大脑前动脉。对于这些病变,许多人倾向于采用大脑半球间入路,但这种手术走廊并非没有风险,因为可能会发生静脉梗塞和皮质损伤:临床表现:我们介绍了一种采用经皮质入路切除巨大双叶镰状脑膜瘤的替代技术,患者是一名68岁的女性,两年来出现进行性失语、尿失禁和双下肢无力。患者接受了单侧右额叶开颅手术和右额叶上回皮质切除术,安全地切除了整个肿瘤。患者对手术耐受良好,顺利出院回家。病理结果显示病变为非典型脑膜瘤,随后她接受了分次放疗辅助治疗。随访两年,她没有出现神经功能障碍,术后从未出现癫痫发作,也没有肿瘤复发的迹象:结论:经皮质方法可作为切除镰状脑膜瘤的一种安全替代方法,不会给患者增加过大的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Transcortical resection of a giant bilobed falcine meningioma.

Introduction: Falcine meningiomas present significant surgical challenges because they often involve the falx bilaterally, are concealed by a significant amount of normal brain parenchyma and are frequently deep in location and in close proximity to the anterior cerebral arteries. Many prefer the interhemispheric approach for these lesions, but this operative corridor is not without risk as venous infarctions and cortical injury can occur.

Clinical presentation: We present an alternative technique utilizing a transcortical approach to resect a giant, bilobed falcine meningioma in a 68-year-old female who presented with progressive abulia, urinary incontinence, and bilateral lower extremity weakness over 2 years. A unilateral right frontal craniotomy and a corticectomy through the right superior frontal gyrus was used to safely resect the entire tumor. The patient tolerated the procedure well and was discharged home without issue. Pathology demonstrated that the lesion was an atypical meningioma and she subsequently received adjuvant fractionated radiotherapy. At 2-year follow-up, she has no neurologic deficits, never developed any postoperative seizures and has not had any evidence of tumor recurrence.

Conclusion: The transcortical approach can be used as a safe alternative for resecting falcine meningiomas without adding significant undue risk to the patient.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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