Catherine Dollfus, Jérome Le Chenadec, Laurent Mandelbrot, Roland Tubiana, Albert Faye, Maud Brossard, Pierre Frange, Stéphane Blanche, Josiane Warszawski
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引用次数: 0
摘要
在ANRS法国围产期队列中，我们比较了830名接受奈韦拉平(NVP)或齐多夫定产后预防的hiv暴露婴儿的结果。1个月时，NVP组贫血等级≥2的发生率低于齐多夫定组(2.9% vs. 8.0%;P = 0.01)，支持将NVP作为低艾滋病毒感染风险婴儿的首选预防措施。
Improved Hematologic Outcomes in HIV1-Exposed Infants Receiving Nevirapine Compared With Zidovudine for Postnatal Prophylaxis in a High Resource Setting.
In the ANRS French Perinatal Cohort, we compared outcomes in 830 HIV1-exposed infants who received either nevirapine (NVP) or zidovudine postnatal prophylaxis. At 1 month, anemia grade ≥2 was less frequent on NVP than zidovudine (2.9% vs. 8.0%; P = 0.01), favoring the use of NVP as a first choice prophylaxis in infants at low risk of HIV acquisition.
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