肾和肺病理:机制和临床意义。

IF 2 Q3 RESPIRATORY SYSTEM

Multidisciplinary Respiratory Medicine Pub Date : 2022-01-18 eCollection Date: 2022-01-12 DOI:10.4081/mrm.2022.819

Ersilia Satta, Carmelo Alfarone, Alfonso De Maio, Sandro Gentile, Carmine Romano, Mario Polverino, Francesca Polverino

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引用次数: 0

摘要

肾和肺在胎儿时期就开始了密切的生理关系，目的是保持体内的稳态平衡。从病理学角度来看，肾脏可能受到炎症介质或与原发性肺部疾病相关的免疫介导因子的损害，或者相反，可能是肾脏疾病导致肺损伤。非免疫机制经常涉及肾脏和肺部疾病，正如在慢性疾病中观察到的那样。这种相声具有临床和治疗意义。这篇综述的目的是描述生理和病理条件下的肺肾联系。

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Kidney and lung in pathology: mechanisms and clinical implications.

There is a close, physiological, relationship between kidney and lung that begin in the fetal age, and is aimed to keep homeostatic balance in the body. From a pathological point of view, the kidneys could be damaged by inflammatory mediators or by immune-mediated factors linked to a primary lung disease or, conversely, it could be the kidney disease that causes lung damage. Non-immunological mechanisms are frequently involved in renal and pulmonary diseases, as observed in chronic conditions. This crosstalk have clinical and therapeutic consequences. This review aims to describe the pulmonary-renal link in physiology and in pathological conditions.

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来源期刊

Multidisciplinary Respiratory Medicine 医学-呼吸系统

CiteScore

4.40

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Multidisciplinary Respiratory Medicine is the official journal of the Italian Respiratory Society - Società Italiana di Pneumologia (IRS/SIP). The journal publishes on all aspects of respiratory medicine and related fields, with a particular focus on interdisciplinary and translational research. The interdisciplinary nature of the journal provides a unique opportunity for researchers, clinicians and healthcare professionals across specialties to collaborate and exchange information. The journal provides a high visibility platform for the publication and dissemination of top quality original scientific articles, reviews and important position papers documenting clinical and experimental advances.