{"title":"横波速度对多囊卵巢综合征的诊断价值。","authors":"Turkan Gursu, Halime Cevik, Güldeniz Aksan Desteli, Birnur Yilmaz, Tevfik Berk Bildaci, Alper Eraslan","doi":"10.15557/JoU.2021.0047","DOIUrl":null,"url":null,"abstract":"<p><p><b>Aim:</b> In polycystic ovarian syndrome, the ovaries become stiffer due to chronic anovulation. We aimed to compare tissue elasticity in terms of shear wave velocities measured using acoustic radiation force impulse imaging technique between the ovaries of polycystic ovarian syndrome women and non-polycystic ovarian syndrome women. <b>Material and methods:</b> The study was designed as a retrospective data analysis of women who underwent transvaginal ultrasound and acoustic radiation force impulse imaging in a university hospital between July 2014 and March 2015, for various reasons. There were 32 polycystic ovarian syndrome patients and 32 patients without a diagnosis of polycystic ovarian syndrome. Age, body mass index, fasting glucose levels, cycle day 3 follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, prolactin, antimullerian hormone levels, and menstrual patterns with clinical hyperandrogenism were evaluated. On the menstrual cycle days 2-4, by performing a transvaginal ultrasound scan, the ovarian volumes and antral follicle counts in both ovaries were recorded for each woman. The ultrasound system was converted into the elastography mode, and acoustic radiation force impulse imaging was performed. Shear wave velocity (m/sec) was measured at least 5 times for each ovary, and the mean value was calculated for each polycystic ovarian syndrome and non-polycystic ovarian syndrome woman. <b>Results:</b> Age, body mass index, fasting glucose levels, cycle day 3 follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, and prolactin levels were similar between the groups (<i>p</i> >0,05). Antimullerian hormone levels, antral follicle counts, and mean ovarian volumes were statistically different between the groups (<i>p</i> <0,05). Mean shear wave velocity values for both ovaries were 2.12 ± 0.82 (0.78-4.9) m/sec in the polycystic ovarian syndrome group, and 1.18 ± 0.41 (0.77-2.0) m/sec in the non-polycystic ovarian syndrome group, which was statistically significantly different (<i>p</i> = 0.016). <b>Conclusion:</b> In our study, we found significantly higher shear wave velocity levels in polycystic ovarian syndrome women than non-polycystic ovarian syndrome women, which indicates an impact of the condition on shear wave velocity. The increased acoustic frequencies cause a decreased response in time to transition, and motion becomes out of phase; in other words, scattered waves are faster in stiffer ovaries. Our results are thus compatible with the pathophysiology of the disease. Shear wave velocity is a beneficial tool for evaluating ovarian elasticity in polycystic ovarian syndrome patients in whom the levels are found to be significantly higher than non-polycystic ovarian syndrome women. In light of these findings, shear wave velocity is expected to be slower than polycystic ovarian syndrome levels in ovulatory women.</p>","PeriodicalId":45612,"journal":{"name":"Journal of Ultrasonography","volume":"21 87","pages":"e277-e281"},"PeriodicalIF":1.3000,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/11/dd/jou-21-87-e277.PMC8678642.pdf","citationCount":"0","resultStr":"{\"title\":\"Diagnostic value of shear wave velocity in polycystic ovarian syndrome.\",\"authors\":\"Turkan Gursu, Halime Cevik, Güldeniz Aksan Desteli, Birnur Yilmaz, Tevfik Berk Bildaci, Alper Eraslan\",\"doi\":\"10.15557/JoU.2021.0047\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Aim:</b> In polycystic ovarian syndrome, the ovaries become stiffer due to chronic anovulation. We aimed to compare tissue elasticity in terms of shear wave velocities measured using acoustic radiation force impulse imaging technique between the ovaries of polycystic ovarian syndrome women and non-polycystic ovarian syndrome women. <b>Material and methods:</b> The study was designed as a retrospective data analysis of women who underwent transvaginal ultrasound and acoustic radiation force impulse imaging in a university hospital between July 2014 and March 2015, for various reasons. There were 32 polycystic ovarian syndrome patients and 32 patients without a diagnosis of polycystic ovarian syndrome. Age, body mass index, fasting glucose levels, cycle day 3 follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, prolactin, antimullerian hormone levels, and menstrual patterns with clinical hyperandrogenism were evaluated. On the menstrual cycle days 2-4, by performing a transvaginal ultrasound scan, the ovarian volumes and antral follicle counts in both ovaries were recorded for each woman. The ultrasound system was converted into the elastography mode, and acoustic radiation force impulse imaging was performed. Shear wave velocity (m/sec) was measured at least 5 times for each ovary, and the mean value was calculated for each polycystic ovarian syndrome and non-polycystic ovarian syndrome woman. <b>Results:</b> Age, body mass index, fasting glucose levels, cycle day 3 follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, and prolactin levels were similar between the groups (<i>p</i> >0,05). Antimullerian hormone levels, antral follicle counts, and mean ovarian volumes were statistically different between the groups (<i>p</i> <0,05). Mean shear wave velocity values for both ovaries were 2.12 ± 0.82 (0.78-4.9) m/sec in the polycystic ovarian syndrome group, and 1.18 ± 0.41 (0.77-2.0) m/sec in the non-polycystic ovarian syndrome group, which was statistically significantly different (<i>p</i> = 0.016). <b>Conclusion:</b> In our study, we found significantly higher shear wave velocity levels in polycystic ovarian syndrome women than non-polycystic ovarian syndrome women, which indicates an impact of the condition on shear wave velocity. The increased acoustic frequencies cause a decreased response in time to transition, and motion becomes out of phase; in other words, scattered waves are faster in stiffer ovaries. Our results are thus compatible with the pathophysiology of the disease. Shear wave velocity is a beneficial tool for evaluating ovarian elasticity in polycystic ovarian syndrome patients in whom the levels are found to be significantly higher than non-polycystic ovarian syndrome women. In light of these findings, shear wave velocity is expected to be slower than polycystic ovarian syndrome levels in ovulatory women.</p>\",\"PeriodicalId\":45612,\"journal\":{\"name\":\"Journal of Ultrasonography\",\"volume\":\"21 87\",\"pages\":\"e277-e281\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2021-11-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/11/dd/jou-21-87-e277.PMC8678642.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Ultrasonography\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15557/JoU.2021.0047\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/12/15 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ultrasonography","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15557/JoU.2021.0047","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/12/15 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
摘要
目的:在多囊卵巢综合征中,由于慢性无排卵,卵巢变得僵硬。我们的目的是比较多囊卵巢综合征妇女和非多囊卵巢综合征妇女的卵巢组织弹性剪切波速测量声学辐射力脉冲成像技术。材料与方法:本研究旨在对2014年7月至2015年3月期间在某大学医院接受阴道超声及声辐射力脉冲成像的女性进行回顾性数据分析。多囊卵巢综合征32例,未诊断多囊卵巢综合征32例。评估年龄、体重指数、空腹血糖水平、月经周期第3天促卵泡激素、促黄体生成素、促甲状腺激素、催乳素、抗苗勒管激素水平和临床高雄激素症的月经模式。在月经周期的第2-4天,通过阴道超声扫描,记录每个妇女的卵巢体积和两个卵巢的窦卵泡计数。将超声系统转换为弹性成像模式,进行声辐射力脉冲成像。每个卵巢至少测量5次横波速度(m/sec),并计算每个多囊卵巢综合征和非多囊卵巢综合征女性的平均值。结果:两组患者年龄、体重指数、空腹血糖水平、周期第3天促卵泡激素、促黄体生成素、促甲状腺激素、催乳素水平差异无统计学意义(p > 0.05)。抗苗勒管激素水平、窦卵泡计数和平均卵巢体积在两组间有统计学差异(p p = 0.016)。结论:在我们的研究中,我们发现多囊卵巢综合征女性的剪切波速水平明显高于非多囊卵巢综合征女性,这表明病情对剪切波速的影响。声波频率的增加导致过渡响应时间的降低,运动变得非相;换句话说,在坚硬的卵巢中,散射波更快。因此,我们的结果与疾病的病理生理学是一致的。横波速度是评估多囊卵巢综合征患者卵巢弹性的有益工具,发现其水平明显高于非多囊卵巢综合征女性。根据这些发现,预计在排卵期妇女中,横波速度比多囊卵巢综合征水平慢。
Diagnostic value of shear wave velocity in polycystic ovarian syndrome.
Aim: In polycystic ovarian syndrome, the ovaries become stiffer due to chronic anovulation. We aimed to compare tissue elasticity in terms of shear wave velocities measured using acoustic radiation force impulse imaging technique between the ovaries of polycystic ovarian syndrome women and non-polycystic ovarian syndrome women. Material and methods: The study was designed as a retrospective data analysis of women who underwent transvaginal ultrasound and acoustic radiation force impulse imaging in a university hospital between July 2014 and March 2015, for various reasons. There were 32 polycystic ovarian syndrome patients and 32 patients without a diagnosis of polycystic ovarian syndrome. Age, body mass index, fasting glucose levels, cycle day 3 follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, prolactin, antimullerian hormone levels, and menstrual patterns with clinical hyperandrogenism were evaluated. On the menstrual cycle days 2-4, by performing a transvaginal ultrasound scan, the ovarian volumes and antral follicle counts in both ovaries were recorded for each woman. The ultrasound system was converted into the elastography mode, and acoustic radiation force impulse imaging was performed. Shear wave velocity (m/sec) was measured at least 5 times for each ovary, and the mean value was calculated for each polycystic ovarian syndrome and non-polycystic ovarian syndrome woman. Results: Age, body mass index, fasting glucose levels, cycle day 3 follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, and prolactin levels were similar between the groups (p >0,05). Antimullerian hormone levels, antral follicle counts, and mean ovarian volumes were statistically different between the groups (p <0,05). Mean shear wave velocity values for both ovaries were 2.12 ± 0.82 (0.78-4.9) m/sec in the polycystic ovarian syndrome group, and 1.18 ± 0.41 (0.77-2.0) m/sec in the non-polycystic ovarian syndrome group, which was statistically significantly different (p = 0.016). Conclusion: In our study, we found significantly higher shear wave velocity levels in polycystic ovarian syndrome women than non-polycystic ovarian syndrome women, which indicates an impact of the condition on shear wave velocity. The increased acoustic frequencies cause a decreased response in time to transition, and motion becomes out of phase; in other words, scattered waves are faster in stiffer ovaries. Our results are thus compatible with the pathophysiology of the disease. Shear wave velocity is a beneficial tool for evaluating ovarian elasticity in polycystic ovarian syndrome patients in whom the levels are found to be significantly higher than non-polycystic ovarian syndrome women. In light of these findings, shear wave velocity is expected to be slower than polycystic ovarian syndrome levels in ovulatory women.