放射性本底对乌克兰不同地区男性性功能的影响。

I I Gorpinchenko, Yu M Gurzhenko, V V Spyrydonenko
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引用次数: 0

摘要

目的:分析切尔诺贝利事故电离辐射暴露区患者性功能障碍的特点。材料与方法:对生活在基辅(波利斯克、切尔诺贝利、伊万科夫、波罗季安卡、维什霍罗德、马卡里夫区)和日托米尔(马林和科罗申区)地区的186人(第一组)进行了性功能研究。对照组由出生和居住在伊万诺-弗兰科夫斯克和切尔诺夫茨地区的人组成(第二组,n = 123)。根据世卫组织和乌克兰卫生部的标准,在门诊基础上进行了诊断。结果:对已获得的研究结果进行分析,I组出现性功能障碍患者的比例(82.3%)明显高于II组(44.7%),差异有统计学意义(p < 0.01)。精神病理障碍患者分别为60.2%和41.4% (p < 0.01)。在接受调查的暴露于电离辐射的男性中,有25.8%的人抱怨性欲下降,其中6.5%的人担心性欲急剧下降。在pii组患者中,该指标分别为14.6%和3.3%。ICEF问卷“libido”积分指数组间差异有统计学意义(分别为9.23±0.89和12.22±1.26,p < 0.05)。在因切尔诺贝利事故而暴露于电离辐射的病人中,睾丸激素浓度下降,卵泡刺激素、黄体生成素以及制造性激素的球蛋白含量增加。ⅰ组患者勃起功能障碍发生率为58.1%,ⅱ组为35.0% (p < 0.01)。在ICEF调查问卷的整体指标组之间的差异是“性欲”领域的1.3倍。对于其他域名- 1.5-1.6倍。生活在基辅和日托米尔地区的男性,勃起功能障碍发生得更早,其特点是比出生和生活在伊万诺-弗兰科夫斯克和切尔诺夫茨地区的人更严重。在正常勃起率低(I组和II组分别为3.8%和13.3%)和存在中度/重度ED的高百分比(分别为71.0%和45.5%)方面,I组患者的特征数据明显差于II组患者(p < 0.01)。性高潮病理检出率分别为40.3%和25.2% (p < 0.01)。以生活质量指数衡量存在性功能障碍情况下,i组患者的生活质量指数为4.7±0.4,II组患者的生活质量指数为3.9±0.2 (p < 0.05)。结论:所获得的数据表明,出生和生活在受切尔诺贝利事故辐射污染地区的男性性功能受到更严重侵犯的趋势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
INFLUENCE OF RADIOACTIVE BACKGROUND ON SEXUAL FUNCTION IN MEN FROM DIFFERENT REGIONS OF UKRAINE.

Objective: The article attempts to analyze the nature of sexual dysfunctions in patients living in areas exposed toionizing radiation as a result of the Chornobyl accident.

Materials and methods: A study of sexual function was carried out in 186 people (group I) living in the territoriesof Kyiv (Polisske, Chornobyl, Ivankiv, Borodianka, Vyshhorod, Makariv districts) and Zhytomyr (Malyn and Korostendistricts) regions. The control group consisted of persons who were born and lived on the territory of Ivano-Frankivsk and Chernivtsi regions (group II, n = 123). Diagnostics was carried out on an outpatient basis in accor-dance with the standards of the WHO and the Ministry of Health of Ukraine.

Results: Analyzing the obtained research results, a significantly larger number of patients with sexual dysfunctionwas identified in group I (82.3 %) than in group II (44.7 %) (р < 0.01). Psychopathological disorders disturbed,respectively, 60.2 % and 41.4 % (p < 0.01). Complaints of decreased libido were presented by 25.8 % of the surveyedmen exposed to ionizing radiation, and 6.5 % of them were concerned about a sharp depression of libido. In groupII patients, this indicator was 14.6 % and 3.3 %, respectively. The integral index of «libido» of the ICEF question-naire revealed a statistically significant difference between the groups (9.23 ± 0.89 and 12.22 ± 1.26, respectively;р < 0.05). In patients exposed to ionizing radiation as a result of the Chornobyl accident, the concentration oftestosterone decreases, and the content of FSH, LH, as well as globulin, which makes sex hormones, increases.Erectile dysfunction in patients of group I was detected in 58.1 % of men, and in patients of group II - 35.0 % (р < 0.01).The difference in the integral indicators of the ICEF questionnaire between the groups was 1.3 times behind the«libido» domain. For other domains - by 1.5-1.6 times. In men living in the territories of Kyiv and Zhytomyr regions,erectile dysfunction occurs earlier and is characterized by a more severe course than in people born and lived in theterritory of Ivano-Frankivsk and Chernivtsi regions. Both in terms of low rates of normal erection (in patients ofgroups I and II, respectively 3.8 % and 13.3 %), and for high percentages of existing moderate/severe ED (respec-tively 71.0 % and 45.5 %), persons from group I are characterized by significantly worse data than persons fromgroup II (р < 0.01). Orgasm pathology was found in 40.3 % of patients in group I and in 25.2 % of patients in groupII (р < 0.01). The quality of life index according to the QoL index in the context of existing sexual disorders in groupI of patients was 4.7 ± 0.4, in patients of group II - 3.9 ± 0.2 (р < 0.05).

Conclusions: The data obtained indicate a tendency for a more significant violation of sexual functions in men whowere born and lived in territories exposed to radioactive contamination as a result of the Chornobyl accident.

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Problemy radiatsiinoi medytsyny ta radiobiolohii
Problemy radiatsiinoi medytsyny ta radiobiolohii Medicine-Radiology, Nuclear Medicine and Imaging
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