Ibrahim Hadadi, William Rae, Jillian Clarke, Mark McEntee, Ernest Ekpo
{"title":"乳腺癌在致密和非致密乳房的检测:诊断信心和疗效的标志。","authors":"Ibrahim Hadadi, William Rae, Jillian Clarke, Mark McEntee, Ernest Ekpo","doi":"10.1177/20584601211072279","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The impact of radiologists' characteristics has become a major focus of recent research. However, the markers of diagnostic efficacy and confidence in dense and non-dense breasts are poorly understood.</p><p><strong>Purpose: </strong>This study aims to assess the relationship between radiologists' characteristics and diagnostic performance across dense and non-dense breasts.</p><p><strong>Materials and methods: </strong>Radiologists specialising in breast imaging (<i>n</i> = 128) who had 0.5-40 (13±10.6) years of experience reading mammograms were recruited. Participants independently interpreted a test set containing 60 digital mammograms (40 normal and 20 abnormal) with similarly distributed breast densities. Diagnostic performance measures were analysed via Jamovi software (version 1.6.22).</p><p><strong>Results: </strong>In dense breasts, breast-imaging fellowship completion significantly improved specificity (<i>p</i> = 0.004), location sensitivity (<i>p</i> = 0.01) and the area under the curve (AUC) of the receiver operating characteristic (<i>p</i> = 0.03). Only participation in BreastScreen reading significantly improved all performance metrics: specificity (<i>p</i> = 0.04), sensitivity (<i>p</i> = 0.005), location sensitivity (<i>p</i> < 0.001) and AUC (<i>p</i> < 0.001). Reading > 100 mammograms weekly significantly improved sensitivity (<i>p</i> = 0.03), location sensitivity (<i>p</i> = 0.001), and AUC (<i>p</i> = 0.03).In non-dense breasts, breast fellowship completion significantly improved sensitivity (<i>p</i> = 0.02), location sensitivity (<i>p</i> = 0.04) and AUC (<i>p</i> = 0.002). Participation in BreastScreen reading and reading > 100 mammograms weekly significantly improved only sensitivity (<i>p</i> = 0.002 and <i>p</i> = 0.003, respectively) and location sensitivity (<i>p</i> < 0.001 and <i>p</i> < 0.001, respectively).</p><p><strong>Conclusion: </strong>Participating in screening programs, breast fellowships and reading > 100 mammograms weekly are important indicators of the diagnostic performance of radiologists across dense and non-dense breasts. In dense breasts, optimal performance resulted from participation in a breast screening program.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.9000,"publicationDate":"2022-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/97/ce/10.1177_20584601211072279.PMC8801646.pdf","citationCount":"2","resultStr":"{\"title\":\"Breast cancer detection across dense and non-dense breasts: Markers of diagnostic confidence and efficacy.\",\"authors\":\"Ibrahim Hadadi, William Rae, Jillian Clarke, Mark McEntee, Ernest Ekpo\",\"doi\":\"10.1177/20584601211072279\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The impact of radiologists' characteristics has become a major focus of recent research. However, the markers of diagnostic efficacy and confidence in dense and non-dense breasts are poorly understood.</p><p><strong>Purpose: </strong>This study aims to assess the relationship between radiologists' characteristics and diagnostic performance across dense and non-dense breasts.</p><p><strong>Materials and methods: </strong>Radiologists specialising in breast imaging (<i>n</i> = 128) who had 0.5-40 (13±10.6) years of experience reading mammograms were recruited. Participants independently interpreted a test set containing 60 digital mammograms (40 normal and 20 abnormal) with similarly distributed breast densities. Diagnostic performance measures were analysed via Jamovi software (version 1.6.22).</p><p><strong>Results: </strong>In dense breasts, breast-imaging fellowship completion significantly improved specificity (<i>p</i> = 0.004), location sensitivity (<i>p</i> = 0.01) and the area under the curve (AUC) of the receiver operating characteristic (<i>p</i> = 0.03). Only participation in BreastScreen reading significantly improved all performance metrics: specificity (<i>p</i> = 0.04), sensitivity (<i>p</i> = 0.005), location sensitivity (<i>p</i> < 0.001) and AUC (<i>p</i> < 0.001). Reading > 100 mammograms weekly significantly improved sensitivity (<i>p</i> = 0.03), location sensitivity (<i>p</i> = 0.001), and AUC (<i>p</i> = 0.03).In non-dense breasts, breast fellowship completion significantly improved sensitivity (<i>p</i> = 0.02), location sensitivity (<i>p</i> = 0.04) and AUC (<i>p</i> = 0.002). Participation in BreastScreen reading and reading > 100 mammograms weekly significantly improved only sensitivity (<i>p</i> = 0.002 and <i>p</i> = 0.003, respectively) and location sensitivity (<i>p</i> < 0.001 and <i>p</i> < 0.001, respectively).</p><p><strong>Conclusion: </strong>Participating in screening programs, breast fellowships and reading > 100 mammograms weekly are important indicators of the diagnostic performance of radiologists across dense and non-dense breasts. In dense breasts, optimal performance resulted from participation in a breast screening program.</p>\",\"PeriodicalId\":72063,\"journal\":{\"name\":\"Acta radiologica open\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2022-01-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/97/ce/10.1177_20584601211072279.PMC8801646.pdf\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta radiologica open\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/20584601211072279\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta radiologica open","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/20584601211072279","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
Breast cancer detection across dense and non-dense breasts: Markers of diagnostic confidence and efficacy.
Background: The impact of radiologists' characteristics has become a major focus of recent research. However, the markers of diagnostic efficacy and confidence in dense and non-dense breasts are poorly understood.
Purpose: This study aims to assess the relationship between radiologists' characteristics and diagnostic performance across dense and non-dense breasts.
Materials and methods: Radiologists specialising in breast imaging (n = 128) who had 0.5-40 (13±10.6) years of experience reading mammograms were recruited. Participants independently interpreted a test set containing 60 digital mammograms (40 normal and 20 abnormal) with similarly distributed breast densities. Diagnostic performance measures were analysed via Jamovi software (version 1.6.22).
Results: In dense breasts, breast-imaging fellowship completion significantly improved specificity (p = 0.004), location sensitivity (p = 0.01) and the area under the curve (AUC) of the receiver operating characteristic (p = 0.03). Only participation in BreastScreen reading significantly improved all performance metrics: specificity (p = 0.04), sensitivity (p = 0.005), location sensitivity (p < 0.001) and AUC (p < 0.001). Reading > 100 mammograms weekly significantly improved sensitivity (p = 0.03), location sensitivity (p = 0.001), and AUC (p = 0.03).In non-dense breasts, breast fellowship completion significantly improved sensitivity (p = 0.02), location sensitivity (p = 0.04) and AUC (p = 0.002). Participation in BreastScreen reading and reading > 100 mammograms weekly significantly improved only sensitivity (p = 0.002 and p = 0.003, respectively) and location sensitivity (p < 0.001 and p < 0.001, respectively).
Conclusion: Participating in screening programs, breast fellowships and reading > 100 mammograms weekly are important indicators of the diagnostic performance of radiologists across dense and non-dense breasts. In dense breasts, optimal performance resulted from participation in a breast screening program.
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