西班牙11个急诊科治疗药物中毒的特点:按性别进行的差异分析。

IF 2.2 4区 医学 Q3 SUBSTANCE ABUSE
Miguel Galicia, Dima Ibrahim-Achi, Òscar Miró, August Supervía, Jordi Puiguriguer, María Ángeles Leciñena, María José Venegas de L'Hotellerie, Beatriz Martín-Pérez, Ana Ferrer, Guillermo Burillo-Putze
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引用次数: 0

摘要

为了从性别角度确定急诊科治疗的药物中毒的社会人口统计学、临床、应急管理和严重程度差异,在24个月内(2017年8月至2019年7月)记录了11名西班牙急诊科患者的数据。中毒的严重程度按性别进行比较,并基于综合不良事件(经口气管插管、心肺骤停、重症监护住院和死亡)。我们纳入了4526名患者(男性占75.5%),平均年龄为33岁。最常见的药物是:可卡因(47.8%)、大麻(44.4%)和苯丙胺(25.5%)。男性比女性摄入更多的GHB(5.6%对1.9%,p<0.001),更少的苯二氮卓类药物(8.0%对11.1%,p=.002)和酒精(57.2%对61.2%,p=.028),其他类型的药物没有差异。男性表现出更严重的心动过缓(OR=4.39,95%CI=1.03-18.7)、胸痛(OR=1.72,95%CI=1.27-2.35)和症状性高血压(OR=1.56,95%CI=1.06-2.30),焦虑(OR=0.74,95%CI=0.61-0.89)和呕吐(OR=0.64,CI95%=0.51-0.80)更少。男性出现更多的联合不良事件(3.1%对2.0%,p=0.047)和更多的插管(1.9%对1.0%,p=0.044),在调整后的模型中没有显著差异(OR=1.349,95%CI=0.827-2.202和OR=1.371,95%CI0.700-2.685)。12名患者死亡(0.3%),性别差异无统计学意义。急诊室的药物中毒情况因性别而异。GHB、苯二氮卓类药物和酒精在男性中的发病率高于女性。心血管症状在男性中更普遍,而焦虑和呕吐在女性中更常见,这不能用社会人口特征或所用药物的差异来解释。中毒发作的严重程度没有差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Characteristics of drug poisonings treated in eleven Spanish emergency departments: Differentiated analysis by sex.

In order to identify the sociodemographic, clinical, emergency management and severity differences of drug poisoning treated in Emergency Departments (ED) from a gender perspective, data on patients from 11 Spanish EDs were recorded over 24 months (August 2017-July 2019). The severity of intoxication was compared by sex and was based on the combined adverse event (orotracheal intubation, cardiorespiratory arrest, intensive care hospitalization, and death). We included 4,526 patients (men 75.5%), with a mean age of 33 years. The most frequent drugs were: cocaine (47.8%), cannabis (44.4%) and amphetamines (25.5%). Men consumed more GHB (5.6% vs. 1.9%, p < .001) and less benzodiazepines (8.0% vs. 11.1%, p = .002) and alcohol (57.2% vs. 61.2%, p = .028) than women, with no differences in other types of drugs. Men presented significantly more severe bradycardia (OR = 4.39, 95%CI = 1.03-18.7), chest pain (OR = 1.72, 95%CI = 1.27-2.35) and symptomatic hypertension (OR = 1.56, 95%CI = 1.06-2.30) and less anxiety (OR = 0.74, 95%CI = 0.61-0.89) and vomiting (OR = 0.64, CI95% = 0.51-0.80). Men had more combined adverse events (3.1% vs. 2.0%, p = .047) and a greater intubations (1.9% vs. 1.0%, p = .044), with no significant differences in the adjusted model (OR = 1.349, 95%CI = 0.827-2.202 and OR = 1.371, 95%CI = 0.700-2.685, respectively). Twelve patients died (0.3%), with no differences according to sex. Drug intoxications attended in the ED differ according to sex. GHB, benzodiazepines and alcohol are more frequently involved in men than women. Cardiovascular symptomatology is more prevalent in men, while anxiety and vomiting are more frequent in women, which cannot be explained by differences in sociodemographic characteristics or the drugs used. There were no differences in the severity of the intoxication episodes.

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来源期刊
Adicciones
Adicciones SUBSTANCE ABUSE-
CiteScore
4.00
自引率
10.00%
发文量
36
审稿时长
>12 weeks
期刊介绍: Adicciones publica artículos originales sobre el tratamiento, la prevención, estudios básicos y descriptivos en el campo de las adicciones, como son las drogas ilegales, el alcohol, el tabaco o cualquier otra adicción, procedentes de distintas disciplinas (medicina, psicología, investigación básica, investigación social, etc.). Todos los artículos son seleccionados después de pasar un proceso de revisión anónimo hecho por expertos en ese tema.
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