辉瑞/BioNTech公司接种SARS-CoV-2疫苗后的无菌性脑膜炎。

IF 1.6 4区医学 Q2 Medicine

Acta Clinica Belgica Pub Date : 2022-12-01 Epub Date: 2021-12-09 DOI:10.1080/17843286.2021.2015101

Valérie Dupon, Stijn Arnaert, Eline Van Haute, Friedel Vulsteke, Günter Diet, Gert De Schoenmakere

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引用次数: 5

摘要

目的:无菌性脑膜炎是辉瑞/BioNTech公司接种SARS-CoV-2疫苗后罕见但可能出现的严重副作用。病例介绍:最近报道了首例接种mRNA-BNT162b2 SARS-CoV-2(辉瑞/BioNTech)疫苗后发生的无菌性脑膜炎病例。我们报告了一例34岁无相关病史的女性在第二次辉瑞/BioNTech疫苗接种后发生无菌性脑膜炎的病例。她在急诊科就诊前5天因严重头痛和发烧入院。对临床问题进行广泛的检查可以缩小鉴别诊断的范围。甲强的松龙治疗后症状消失。结论:本病例强调了接种疫苗后罕见但重要的副作用，初级医生和神经科医生应该意识到这一点，以便识别和有效地管理这些患者。

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Aseptic meningitis after SARS-CoV-2 Pfizer/BioNTech vaccination.

ABSTRACT Objective Aseptic meningitis is a rare, but possible severe side effect after SARS-CoV-2 Pfizer/BioNTech vaccination. Case Presentation Recently, a first case of aseptic meningitis after the first shot of mRNA-BNT162b2 SARS-CoV-2 (Pfizer/BioNTech) vaccine was reported. We present the first case of a 34-year-old woman without relevant medical history developing aseptic meningitis after her 2nd Pfizer/BioNTech vaccination. She was admitted with severe headache and fever for 5 days prior to her presentation at the emergency department. An extensive work-up of the clinical problem could narrow the differential diagnosis. Symptoms resolved after methylprednisolone therapy. Conclusion This case highlights a rare but important side effect after vaccination that primary physicians and neurologists should be aware of in order to identify and efficiently manage these patients.

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来源期刊

Acta Clinica Belgica 医学-医学：内科

CiteScore

2.90

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Acta Clinica Belgica: International Journal of Clinical and Laboratory Medicine primarily publishes papers on clinical medicine, clinical chemistry, pathology and molecular biology, provided they describe results which contribute to our understanding of clinical problems or describe new methods applicable to clinical investigation. Readership includes physicians, pathologists, pharmacists and physicians working in non-academic and academic hospitals, practicing internal medicine and its subspecialties.