颈动脉体炎症:在缺氧和抗炎反射中的作用。

IF 10.3

Physiology (Bethesda, Md.) Pub Date : 2022-05-01 Epub Date: 2021-12-06 DOI:10.1152/physiol.00031.2021

Rodrigo Iturriaga, Rodrigo Del Rio, Julio Alcayaga

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引用次数: 10

摘要

新的证据表明，颈动脉体(CB)化学感受器可能感知全身炎症分子，是抗炎反射的传入臂。此外，在持续和间歇性缺氧后，脑脊膜内的促炎环境参与了脑脊膜对氧的化学感觉反应的增强。在这篇综述中，我们重点关注CBs在炎症性疾病中的生理病理参与，如败血症和间歇性缺氧。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Carotid Body Inflammation: Role in Hypoxia and in the Anti-inflammatory Reflex.

Emergent evidence indicates that the carotid body (CB) chemoreceptor may sense systemic inflammatory molecules and is an afferent arm of the anti-inflammatory reflex. Moreover, a proinflammatory milieu within the CB is involved in the enhanced CB chemosensory responsiveness to oxygen following sustained and intermittent hypoxia. In this review, we focus on the physiopathological participation of CBs in inflammatory diseases, such as sepsis and intermittent hypoxia.

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来源期刊

Physiology (Bethesda, Md.)

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