膜张力。

4区生物学 Q4 Biochemistry, Genetics and Molecular Biology

Current topics in membranes Pub Date : 2021-01-01 Epub Date: 2021-11-02 DOI:10.1016/bs.ctm.2021.09.002

Pei-Chuan Chao, Frederick Sachs

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引用次数: 1

摘要

细胞膜起屏障作用，限制可扩散分子的交换速率。膜张力调节许多重要的细胞功能，包括形状变化和运动、细胞信号、内吞作用和机械感觉。张力反映了脂质双分子层、细胞骨架和细胞外基质所产生的力。在类流体双层模型中，膜张力被认为是均匀的，因此是瞬时传播的。在这篇综述中，我们讨论了测量平均膜张力的技术，以及如何解决不同组分的应力，并考虑了双层非均质性的作用。

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Membrane tension.

The cell membrane serves as a barrier that restricts the rate of exchange of diffusible molecules. Tension in the membrane regulates many crucial cell functions involving shape changes and motility, cell signaling, endocytosis, and mechanosensation. Tension reflects the forces contributed by the lipid bilayer, the cytoskeleton, and the extracellular matrix. With a fluid-like bilayer model, membrane tension is presumed uniform and hence propagated instantaneously. In this review, we discuss techniques to measure the mean membrane tension and how to resolve the stresses in different components and consider the role of bilayer heterogeneity.

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来源期刊

Current topics in membranes 生物-生化与分子生物学

CiteScore

3.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology.