重症监护病房的抗凝监测。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-04-01 DOI:10.1097/CNQ.0000000000000394

Brian W Gilbert, Jacob A Reeder, Tessa R Reynolds, Caitlynn A Tabaka, Megan A Rech

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引用次数: 2

摘要

危重症患者经常表现出可变的低凝和高凝后遗症，需要加强监测和抗凝药物治疗，以防止或治疗不适当的凝块形成。了解凝血级联的各个阶段以及每种药物在何处发挥其治疗作用是非常必要的。常用的凝血试验用于监测凝血级联的区域和抗凝药物治疗的效果。许多新的凝血试验也在开发中。这篇叙述性综述的目的是评估在重症监护病房监测抗凝的常用凝血试验。

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Anticoagulation Monitoring in the Intensive Care Unit.

Patients with critical illness often display variable hypo- and hypercoagulable sequalae requiring intense monitoring and anticoagulation pharmacotherapy to prevent or treat inappropriate clot formation. It is imperative to understand the various stages of the clotting cascade and where each pharmacotherapy agent exerts its therapeutic effect. Common coagulation tests are utilized to monitor the areas of the clotting cascade and the effects that anticoagulant pharmacotherapy exhibits. Many novel coagulation tests are also in development. The purpose of this narrative review is to evaluate commonly utilized coagulation tests that monitor anticoagulation while in the intensive care unit.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.