1型糖尿病的不典型表现。

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL
Archive of clinical cases Pub Date : 2021-12-29 eCollection Date: 2021-01-01 DOI:10.22551/2021.32.0803.10185
Brandon W Knopp, Parvathi Perumareddi
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引用次数: 0

摘要

1型和2型糖尿病在历史上被描述为发生在不同的患者人群中;然而,随着糖尿病患病率的增加,非典型人口统计学变得越来越频繁,跨越了年龄的界限。其中一些病例的临床诊断可能具有挑战性,因为患者的症状和进展可能不同于1型和2型糖尿病的标准特征。我们的病例是一个1型糖尿病患者的典型表现,其特征通常与2型糖尿病相关。这样的患者表现并不常见,我们的患者表现出2型糖尿病的“教科书”特征。当患者首次被诊断为2型糖尿病时,患者60岁,体重指数在30左右,在几个月的时间里症状逐渐出现。患者在64岁时,经过一年的血糖控制下降,GAD65自身抗体检测呈阳性,重新评估并归类为1型糖尿病患者。随后的胰岛素注射解决了他的糖尿病相关并发症,包括多尿、虚弱和体重减轻,并改善了他的血糖控制。本病例为1型糖尿病的不寻常临床表现提供了一个例子,并有助于提高对糖尿病非典型表现的认识,以提高早期阶段的准确分类。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An atypical presentation of type 1 diabetes.

Type 1 and type 2 diabetes have been described historically as occurring in distinct patient populations; however, atypical demographics are becoming more frequent as the prevalence of diabetes increases, crossing boundaries of ages. Some of these cases can be challenging to diagnose clinically as the patient symptomatology and progression can differ from the standard features of type 1 and 2 diabetes. Our case is an example of a patient whose type 1 diabetes presented atypically with characteristics often associated with type 2 diabetes. Patient presentations such as this are uncommon, with our patient having presented with the "textbook" characteristics of type 2 diabetes. When first diagnosed with diabetes mellitus type 2, the patient was 60 years old, had a BMI around 30 and experienced a gradual onset of symptoms over the course of several months. At the age of 64, the patient tested positive for GAD65 autoantibodies following a year of declining glycemic control and was re-evaluated and classified as a type 1 diabetes patient. Subsequent insulin injections resolved his diabetes-related complications which included polyuria, weakness and weight loss and improved his glycemic control. This case provides an example of an unusual clinical presentation of type 1 diabetes and serves to raise awareness for atypical presentations of diabetes to improve accurate classifications at earlier stages.

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