一吻合术和Roux-en-Y胃旁路术在短期随访中促进相似的体重减轻、患者满意度、生活质量、炎症等级和食管和胃袋细胞损伤。

IF 4.7 Q1 ENDOCRINOLOGY & METABOLISM
Rafael C Katayama, Carlos H Arasaki, Fernando A M Herbella, Ricardo A Neto, Gaspar de Jesus Lopes Filho
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引用次数: 8

摘要

背景:单吻合术胃旁路术(OAGB)比Roux-en-Y胃旁路术(RYGB)更简单;然而,胆道反流可能发生并损害预后。本研究旨在比较OAGB和RYGB的结果。方法:将20例病态肥胖患者前瞻性随机分为OAGB组(n=10)和RYGB组(n=10)。评估术前、术后6个月患者的生活质量(36项简短健康调查[SF-36])、满意度(Visick量表)、体重指数(BMI)。所有患者均于术后3个月和6个月行食管胃十二指肠镜检查并行胃和食管粘膜活检。结果:研究发现术前BMI (OAGB, 43.2 kg/m2;RYGB: 43.1 kg/m2;P=0.90)或术后6个月(OAGB, 32.1 kg/m2;RYGB, 31.8 kg/m2;P = 0.91)。6个月时两组患者的生活质量(4个SF-36领域)改善和满意度无显著差异(P=0.08)。两组患者3个月和6个月时胃(P=0.10)和食管(P=0.76)炎症等级比较,差异均无统计学意义。结论:OAGB和RYGB在术后6个月的体重减轻、患者满意度和生活质量改善方面同样有效。胃袋和食道的炎症程度和细胞损伤相似。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

One-Anastomosis and Roux-en-Y Gastric Bypass Promote Similar Weight Loss, Patient Satisfaction, Quality of Life, Inflammation Grade, and Cellular Damage in the Esophagus and Gastric Pouch in a Short-term Follow-up.

One-Anastomosis and Roux-en-Y Gastric Bypass Promote Similar Weight Loss, Patient Satisfaction, Quality of Life, Inflammation Grade, and Cellular Damage in the Esophagus and Gastric Pouch in a Short-term Follow-up.

Background: One-anastomosis gastric bypass (OAGB) is a simpler procedure than Roux-en-Y gastric bypass (RYGB); however, biliary reflux can occur and impair outcomes. This study aimed to compare outcomes of OAGB and RYGB.

Methods: Twenty patients with morbid obesity were randomized prospectively into two groups: OAGB (n=10) or RYGB (n=10). Quality of life (36-item short-form health survey [SF-36]), satisfaction (Visick scale), and body mass index (BMI) were evaluated before and 6 months after the operation. All patients underwent esophagogastroduodenoscopy with gastric and esophageal mucosal biopsies at 3 and 6 months after their operation.

Results: The study found no significant difference in BMI before surgery (OAGB, 43.2 kg/m2; RYGB, 43.1 kg/m2; P=0.90) or at 6 months postoperative (OAGB, 32.1 kg/m2; RYGB, 31.8 kg/m2; P=0.91). There was no significant difference in improvement of quality of life (four SF-36 domains) or satisfaction (P=0.08) between groups at 6 months. There was no statistical difference between gastric (P=0.10) and esophageal (P=0.76) inflammation grade at three or 6 months between the two groups.

Conclusion: OAGB and RYGB are equally effective in terms of weight loss, patient satisfaction, and quality of life improvement at 6 months after the procedures. Inflammation grade and cellular damage in the gastric pouch and in the esophagus were similar.

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来源期刊
Journal of Obesity & Metabolic Syndrome
Journal of Obesity & Metabolic Syndrome ENDOCRINOLOGY & METABOLISM-
CiteScore
8.30
自引率
9.60%
发文量
39
审稿时长
19 weeks
期刊介绍: The journal was launched in 1992 and diverse studies on obesity have been published under the title of Journal of Korean Society for the Study of Obesity until 2004. Since 2017, volume 26, the title is now the Journal of Obesity & Metabolic Syndrome (pISSN 2508-6235, eISSN 2508-7576). The journal is published quarterly on March 30th, June 30th, September 30th and December 30th. The official title of the journal is now "Journal of Obesity & Metabolic Syndrome" and the abbreviated title is "J Obes Metab Syndr". Index words from medical subject headings (MeSH) list of Index Medicus are included in each article to facilitate article search. Some or all of the articles of this journal are included in the index of PubMed, PubMed Central, Scopus, Embase, DOAJ, Ebsco, KCI, KoreaMed, KoMCI, Science Central, Crossref Metadata Search, Google Scholar, and Emerging Sources Citation Index (ESCI).
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