酒精性肝炎中的细络菌菌血症。

Case Reports in Hepatology Pub Date : 2021-10-13 eCollection Date: 2021-01-01 DOI:10.1155/2021/9947213
Patrick Lee, Brandon K K Fields, Tom Liang, Michael P Dubé, Seth Politano
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引用次数: 5

摘要

细孔菌是人类口腔、肠道和阴道微生物群的共生细菌,很少被确定为临床相关病原体。在这里,我们描述了一个新的情况下,非典型性细孔菌菌血症患者活检证实酒精性肝炎。细络菌种类与自身免疫性肝炎和肝硬化等肝病的疾病严重程度和肝性脑病相关。最近也观察到它们在酒精性肝炎中的丰度增加,已知炎症后感染会影响死亡率。本病例报告强调了严重酒精性肝炎患者肠道生态失调可能导致的临床表现。在易感人群中,早期识别和治疗细络菌血症对患者的生存至关重要,因为这种微生物容易引起危及生命的感染,包括脑膜炎、心内膜炎和骨髓炎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

<i>Veillonella</i> Bacteremia in Alcoholic Hepatitis.

<i>Veillonella</i> Bacteremia in Alcoholic Hepatitis.

Veillonella Bacteremia in Alcoholic Hepatitis.

Veillonella species are commensal bacteria of the human oral, gut, and vaginal microbiota that are rarely identified as clinically relevant pathogens. Here, we describe a novel case of Veillonella atypica bacteremia in a patient with biopsy-proven alcoholic hepatitis. Veillonella species have been correlated with disease severity and hepatic encephalopathy in liver diseases such as autoimmune hepatitis and cirrhosis. Their abundance has also been recently observed to be increased in alcoholic hepatitis, where postinflammatory infections are known to impact mortality. This case report highlights the possible clinical manifestations that result from significant gut dysbiosis in patients with severe alcoholic hepatitis. Early identification and treatment of Veillonella bacteremia in susceptible populations could be crucial to survival given this organism's predilection for causing life-threatening infections, including meningitis, endocarditis, and osteomyelitis.

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