基因组学时代南岛侨民的重建。

4区生物学 Q2 Medicine

Human Biology Pub Date : 2021-10-01 DOI:10.13110/humanbiology.92.4.04

Geoffrey K Chambers, Hisham A Edinur

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引用次数: 6

摘要

《南岛侨民》讲述了5000年前一小群台湾农民如何扩张到占据半个地球的领土。重建他们详细的历史引发了许多学科的学术竞赛。一个大致的正统版本最终出现了，但仍有许多未解之谜。全基因组技术的非凡力量现在已经应用到整个地区的人们身上。这篇综述给出了这个时代的遗传调查，并讨论了它的许多成就，包括揭示了许多意想不到的人口流动模式的细节和这些信息对医学遗传学的意义。

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Reconstruction of the Austronesian Diaspora in the Era of Genomics.

The Austronesian Diaspora is a 5,000-year account of how a small group of Taiwanese farmers expanded to occupy territories reaching halfway around the world. Reconstructing their detailed history has spawned many academic contests across many disciplines. An outline orthodox version has eventually emerged but still leaves many unanswered questions. The remarkable power of whole-genome technology has now been applied to people across the entire region. This review gives an account of this era of genetic investigation and discusses its many achievements, including revelation in detail of many unexpected patterns of population movement and the significance of this information for medical genetics.

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来源期刊

Human Biology 生物-生物学

CiteScore

1.90

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Human Biology publishes original scientific articles, brief communications, letters to the editor, and review articles on the general topic of biological anthropology. Our main focus is understanding human biological variation and human evolution through a broad range of approaches. We encourage investigators to submit any study on human biological diversity presented from an evolutionary or adaptive perspective. Priority will be given to interdisciplinary studies that seek to better explain the interaction between cultural processes and biological processes in our evolution. Methodological papers are also encouraged. Any computational approach intended to summarize cultural variation is encouraged. Studies that are essentially descriptive or concern only a limited geographic area are acceptable only when they have a wider relevance to understanding human biological variation. Manuscripts may cover any of the following disciplines, once the anthropological focus is apparent: human population genetics, evolutionary and genetic demography, quantitative genetics, evolutionary biology, ancient DNA studies, biological diversity interpreted in terms of adaptation (biometry, physical anthropology), and interdisciplinary research linking biological and cultural diversity (inferred from linguistic variability, ethnological diversity, archaeological evidence, etc.).