手术切除食蟹猴(Macaca fascularis)的遥测系统:为期12个月的观察研究。

IF 2.7 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Doo-Wan Cho, Hyoung-Yun Han, Mi-Jin Yang, Dong Ho Woo, Su-Cheol Han, Young-Su Yang
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引用次数: 1

摘要

背景:遥测是一种无线植入装置,用于测量有意识动物的生物信号,通常在研究结束后需要手术将其移除。移除设备后,这些动物要么被用于其他研究,要么被安乐死。病例介绍:在此,我们报告了一只活食蟹猴(Macaca fascicularis)的病例,在手术移除植入的遥测系统后,它被用于整个实验期间,而不是安乐死。使用x线摄影来确定植入遥测装置的状态,随后进行修复手术以移除系统;临床体征被用来保存食蟹猴的生命。观察12个月,观察术后临床体征、饮食、血液学和血清生化。植入物移除后,受试者未观察到异常读数或异常情况。结论:本研究为活食蟹猴在整个研究期间的遥测植入提供了有益的病例报告。我们建议尽量减少这些动物的痛苦,提高它们的福利。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study.

Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study.

Background: Telemetry is a wireless implanted device that measures biological signals in conscious animals and usually requires surgery for its removal when the study is finished. After removing the device, the animals are either used for other studies or euthanatized.

Case presentation: Herein, we report the case of a living cynomolgus monkey (Macaca fascicularis) that was used for the entire experimental period, instead of euthanasia, after surgical removal of an implanted telemetry system. Radiography was used to determine the status of the implanted telemetry, following which, a repair surgery was performed for removing the system; clinical signs were used to preserve the life of the cynomolgus monkey. Postoperative clinical signs, food consumption, hematology, and serum biochemistry were examined during the 12-month observational period. No abnormal readings or conditions were observed in the subject after implant removal.

Conclusions: This study may be a useful case report for living cynomolgus monkeys in telemetry implantations used throughout the study period. We suggest minimizing the suffering and improving the welfare of these animals.

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来源期刊
CiteScore
4.40
自引率
0.00%
发文量
32
审稿时长
8 weeks
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