卢塞恩州立医院在结直肠手术中成功实施捆绑式护理以减少手术部位感染:前瞻性观察研究的研究方案。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2021-09-23 eCollection Date: 2021-01-01 DOI:10.29337/ijsp.150
Stefanie Brunner, Jule Liesenberg, Lana Fourie, Jürg Metzger, Andreas Scheiwiller, Irin Zschokke, Dirk Lehnick, Jörn-Markus Gass
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引用次数: 0

摘要

背景:手术部位感染(SSI)仍是结直肠外科的一个相关问题。本研究旨在实施捆绑护理,以减少结直肠手术中的 SSI:所有在 2018 年 10 月至 2021 年 12 月期间接受结直肠手术的患者都将纳入前瞻性观察研究。由于我们的结直肠束是逐步建立的,因此将把患者分为实施前(2018-2019 年)、实施阶段(2019-2020 年)和实施后阶段(2021 年),以评估所采取的行动的有效性。本研究的主要终点是手术部位感染(SSI)率,次要终点包括 SSI 的潜在风险因素。我们认为,肥胖、年龄、糖尿病、酗酒和吸烟可能会导致 SSI 风险升高:本研究旨在确定卢塞恩州立医院设计并实施的结直肠捆绑疗法是否能显著减少 SSI。此外,还将评估SSI潜在风险因素的影响:试验注册:ClinicalTrials.gov,ID:试验注册:ClinicalTrials.gov,ID:NCT04677686。2020年12月18日回顾性注册:重点:捆绑式护理可减少结直肠手术后手术部位感染的发生。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Implementation of a Bundle of Care in Colorectal Surgery to Reduce Surgical Site Infections Successfully at Cantonal Hospital Lucerne: Study Protocol for a Prospective Observational Study.

Background: Surgical site infections (SSIs) remain a relevant problem in colorectal surgery. The aim of this study is to implement a bundle of care in order to reduce SSIs in colorectal surgery.

Methods: All patients undergoing colorectal surgery between October 2018 and December 2021 will be included in a prospective observational study. Since our colorectal bundle has been established gradually, patients will be grouped in a pre-implementation (2018-2019), implementation (2019-2020) and post implementation phase (2021), in order to assess the effectiveness of the actions undertaken. Primary endpoint of this study will be surgical site infection (SSI) rate, while secondary endpoints encompass potential risk factors for SSIs. We assume that obesity, age, diabetes, alcoholism and smoking may lead to a higher risk for SSIs.

Discussion: This study aims to determine whether the colorectal bundle designed and implemented at Cantonal Hospital Lucerne, will lead to a significant reduction of SSIs. The impact of potential risk factors for SSIs will additionally be evaluated.

Trial registration: ClinicalTrials.gov, ID: NCT04677686. Registered retrospectively 18 December 2020.

Highlights: A bundle of care might reduce the occurence of surgical site infections after colorectal surgery.Analysis of risk factors may detect patient's with high probability of developing surgical site infections.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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