在蛋白质营养不良的小鼠中，当地生产的植物性补品Swathi Savi (Savi)浓缩可改善身体生长、骨骼发育和免疫功能:对对抗儿童营养不良策略的影响。

IF 1.7 4区医学 Q4 NUTRITION & DIETETICS

Ecology of Food and Nutrition Pub Date : 2022-03-01 Epub Date: 2021-09-30 DOI:10.1080/03670244.2021.1977636

Kristen Pinchun Yang, Carmen P Wong, Sunil K Khanna, Tammy M Bray

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引用次数: 0

摘要

儿童营养不良是一项重大的全球挑战。仅印度就有近4600万发育迟缓儿童，占世界总数的三分之一。补充当地生产的食品已被认为是防治儿童营养不良的可持续战略。我们在年轻小鼠中建立了蛋白质营养不良(PM)模型，以评估富含savi的饮食作为对抗印度儿童营养不良的食物补充剂的安全性和有效性。结果表明，喂养富含savi的饲料改善了PM幼鼠的体重、瘦肌肉质量、骨骼和免疫健康。基于我们在小鼠身上的研究结果，我们建议未来进行人体试验，以检验这种补充剂对人类的潜在益处。

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A Locally-Produced Plant-Based Supplement Swathi Savi (SAVI) Enrichment Improves Body Growth, Bone Development, and Immune Functions in Protein Malnourished Mice: Implications for Strategies to Combat Child Malnutrition.

Child malnutrition is a critical global challenge. India alone is home to nearly 46 million stunted children, a third of the world's total. Supplementing locally-produced foods has been acknowledged as a sustainable strategy for combating child malnutrition. We used an established protein malnutrition (PM) model in young mice to evaluate the safety and efficacy of the SAVI-enriched diet as a food supplement to combat child malnutrition in India. Results indicate that feeding the SAVI-enriched diet improves body weight, lean muscle mass, bone, and immune health in PM young mice. Based on the results of our study in mice, we suggest future human trials to examine the supplement's potential benefits for humans.

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来源期刊

Ecology of Food and Nutrition 医学-营养学

CiteScore

3.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Ecology of Food and Nutrition is an international journal of food and nutrition in the broadest sense. The journal publishes peer-reviewed articles on all aspects of food and nutrition -- ecological, biological, and cultural. Ecology of Food and Nutrition strives to become a forum for disseminating scholarly information on the holistic and cross-cultural dimensions of the study of food and nutrition. It emphasizes foods and food systems not only in terms of their utilization to satisfy human nutritional needs and health, but also to promote and contest social and cultural identity. The content scope is thus wide -- articles may focus on the relationship between food and nutrition, food taboos and preferences, ecology and political economy of food, the evolution of human nutrition, changes in food habits, food technology and marketing, food and identity, and food sustainability. Additionally, articles focusing on the application of theories and methods to address contemporary food and nutrition problems are encouraged. Questions of the relationship between food/nutrition and culture are as germane to the journal as analyses of the interactions among nutrition and environment, infection and human health.