Mehmet Doğan, Nurdan Akıcı, Mehmet Emin Diken, Serap Doğan, Begumhan Yilmaz Kardas, Tuncay Dirmenci
{"title":"几种鼠尾草的生物活性。","authors":"Mehmet Doğan, Nurdan Akıcı, Mehmet Emin Diken, Serap Doğan, Begumhan Yilmaz Kardas, Tuncay Dirmenci","doi":"10.1515/znc-2021-0136","DOIUrl":null,"url":null,"abstract":"<p><p>In this study, total phenolic, flavonoid and protein contents, antiradical capacities, antibacterial and cytotoxic properties of five different <i>Salvia</i> species (<i>Salvia macrochlamys</i> Boiss., <i>Salvia kronenburgii</i> Rech.f., <i>Salvia euphratica</i> Montbret. ex Aucher var. <i>euphratica</i>, <i>Salvia huberi</i> Hedge and <i>Salvia kurdica</i> Benth) were investigated. The total phenolic content of the species was in the range of 59.6 ± 20 to 150.1 ± 1.1 mg/g, total flavonoid content in the range of 20.4 ± 2.2 to 38.9 ± 4.1 mg/g, and total protein content in the range of 14.0 ± 0.5 to 22.0 ± 1.1 mg/g. Radical scavenging capacities of the <i>Salvia</i> species were determined in the range of 84.1 ± 4.5 to 96.8 ± 0.1%. Moreover, <i>Salvia</i> extracts showed powerful antibacterial activity against <i>Escherichia coli</i> and <i>Staphylococcus aureus</i> bacteria. Cytotoxic effects of the samples on human lymphocytes were determined by MTS assay and <i>S. kronenburgii</i> and <i>S. euphratica</i> var. <i>euphratica</i> decreased the harmful effects of 2-hydroperoxy-2-methylpropane (tert-butyl hydroper-oxide, t-BOOH) at all time points tested. The highest amounts of rutin hydrate belong to <i>S. kronenburgii</i> and <i>S. euphratica</i> var. <i>euphratica</i>, and the highest amounts of luteolin-7-glucoside belong to <i>S. huberi</i> and <i>S. kronenburgii</i>. Vanillic acid was present only in <i>S. huberi</i> and <i>S. kurdica</i>.</p>","PeriodicalId":49344,"journal":{"name":"Zeitschrift Fur Naturforschung Section C-A Journal of Biosciences","volume":"77 3-4","pages":"133-143"},"PeriodicalIF":2.1000,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Biological activities of some <i>Salvia</i> species.\",\"authors\":\"Mehmet Doğan, Nurdan Akıcı, Mehmet Emin Diken, Serap Doğan, Begumhan Yilmaz Kardas, Tuncay Dirmenci\",\"doi\":\"10.1515/znc-2021-0136\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In this study, total phenolic, flavonoid and protein contents, antiradical capacities, antibacterial and cytotoxic properties of five different <i>Salvia</i> species (<i>Salvia macrochlamys</i> Boiss., <i>Salvia kronenburgii</i> Rech.f., <i>Salvia euphratica</i> Montbret. ex Aucher var. <i>euphratica</i>, <i>Salvia huberi</i> Hedge and <i>Salvia kurdica</i> Benth) were investigated. The total phenolic content of the species was in the range of 59.6 ± 20 to 150.1 ± 1.1 mg/g, total flavonoid content in the range of 20.4 ± 2.2 to 38.9 ± 4.1 mg/g, and total protein content in the range of 14.0 ± 0.5 to 22.0 ± 1.1 mg/g. Radical scavenging capacities of the <i>Salvia</i> species were determined in the range of 84.1 ± 4.5 to 96.8 ± 0.1%. Moreover, <i>Salvia</i> extracts showed powerful antibacterial activity against <i>Escherichia coli</i> and <i>Staphylococcus aureus</i> bacteria. Cytotoxic effects of the samples on human lymphocytes were determined by MTS assay and <i>S. kronenburgii</i> and <i>S. euphratica</i> var. <i>euphratica</i> decreased the harmful effects of 2-hydroperoxy-2-methylpropane (tert-butyl hydroper-oxide, t-BOOH) at all time points tested. The highest amounts of rutin hydrate belong to <i>S. kronenburgii</i> and <i>S. euphratica</i> var. <i>euphratica</i>, and the highest amounts of luteolin-7-glucoside belong to <i>S. huberi</i> and <i>S. kronenburgii</i>. Vanillic acid was present only in <i>S. huberi</i> and <i>S. kurdica</i>.</p>\",\"PeriodicalId\":49344,\"journal\":{\"name\":\"Zeitschrift Fur Naturforschung Section C-A Journal of Biosciences\",\"volume\":\"77 3-4\",\"pages\":\"133-143\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2021-09-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zeitschrift Fur Naturforschung Section C-A Journal of Biosciences\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1515/znc-2021-0136\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/3/28 0:00:00\",\"PubModel\":\"Print\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift Fur Naturforschung Section C-A Journal of Biosciences","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1515/znc-2021-0136","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/3/28 0:00:00","PubModel":"Print","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
In this study, total phenolic, flavonoid and protein contents, antiradical capacities, antibacterial and cytotoxic properties of five different Salvia species (Salvia macrochlamys Boiss., Salvia kronenburgii Rech.f., Salvia euphratica Montbret. ex Aucher var. euphratica, Salvia huberi Hedge and Salvia kurdica Benth) were investigated. The total phenolic content of the species was in the range of 59.6 ± 20 to 150.1 ± 1.1 mg/g, total flavonoid content in the range of 20.4 ± 2.2 to 38.9 ± 4.1 mg/g, and total protein content in the range of 14.0 ± 0.5 to 22.0 ± 1.1 mg/g. Radical scavenging capacities of the Salvia species were determined in the range of 84.1 ± 4.5 to 96.8 ± 0.1%. Moreover, Salvia extracts showed powerful antibacterial activity against Escherichia coli and Staphylococcus aureus bacteria. Cytotoxic effects of the samples on human lymphocytes were determined by MTS assay and S. kronenburgii and S. euphratica var. euphratica decreased the harmful effects of 2-hydroperoxy-2-methylpropane (tert-butyl hydroper-oxide, t-BOOH) at all time points tested. The highest amounts of rutin hydrate belong to S. kronenburgii and S. euphratica var. euphratica, and the highest amounts of luteolin-7-glucoside belong to S. huberi and S. kronenburgii. Vanillic acid was present only in S. huberi and S. kurdica.
期刊介绍：
A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) is an international scientific journal and a community resource for the emerging field of natural and natural-like products. The journal publishes original research on the isolation (including structure elucidation), bio-chemical synthesis and bioactivities of natural products, their biochemistry, pharmacology, biotechnology, and their biological activity and innovative developed computational methods for predicting the structure and/or function of natural products. A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) welcomes research papers in fields on the chemistry-biology boundary which address scientific ideas and approaches to generate and understand natural compounds on a molecular level and/or use them to stimulate and manipulate biological processes.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
