乙肝病毒培养系统的发展

Uirusu Pub Date : 2020-01-01 DOI:10.2222/jsv.70.135

Yuichi Akahori, Makoto Hijikata

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引用次数: 0

摘要

近年来，乙型肝炎病毒(HBV)培养系统的发展已经开始了包括感染步骤在内的HBV生命周期的分子病毒学研究。然而，可能需要更生理条件下HBV生命周期的再现，才能更准确地了解HBV的性质。我们最近开发的HBV培养系统，使用在三维条件下培养的永生化人肝细胞，似乎是实现这一目的的好工具之一。

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[Development of hepatitis B virus culture systems].

Recent development of hepatitis B virus (HBV) culture systems has proceeded the molecular virological studies of the life cycle of HBV including infection step. However, the reproduction of HBV life cycle under the more physiological condition may be required to know the nature of HBV more precisely. The HBV culture system, we recently developed using immortalized human hepatocytes cultured in the three dimensional condition, seemed to be one of good tools for that purpose.

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Uirusu

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