一种特殊的口咽氧合装置,与高流量氧合装置相比,可促进窒息氧合。

IF 3 Q2 MEDICINE, RESEARCH & EXPERIMENTAL
Wolfgang A Wetsch, Daniel C Schroeder, Simon-Richard Finke, David Sander, Hannes Ecker, Bernd W Böttiger, Holger Herff
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引用次数: 3

摘要

在清醒纤维插管或气管插管失败时,应用氧气和无氧氧合可降低因呼吸暂停引起的低氧血症的风险。推荐使用高流量设备,但与中等深口咽氧应用相比,其效果尚不清楚。我们设计了一个实验性的人体模型试验,比较了10 L/min鼻尖供氧(对照组)、10 L/min口咽氧合装置供氧(10 L/min)、20 L/min高流量鼻氧和90%氧(20 L/90%组)、60 L/min高流量鼻氧和45%氧(60 L/45%组)。通过一个特殊适配器的密封面罩供氧以允许光纤进入气道。我们对人体模型的肺进行预充氧,并在接下来的20分钟内测量每种给氧方式的氧水平下降情况。对照组氧含量由基线时的97±1%降至75±1%,口咽氧合装置组降至86±1%。高流量鼻吸氧组,20 L/90%组氧含量为72±1%,60 L/45%组氧含量为44±1%。面罩组氧含量维持在98±0%。综上所述,在这个模拟呼吸暂停氧合的人体研究中,使用密封面罩进行氧气吸入,在20分钟内将测试肺的氧含量保持在98%,口服氧合装置使氧含量达到86%,而所有其他方法导致氧含量下降到75%以下。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A special oropharyngeal oxygenation device to facilitate apneic oxygenation in comparison to high flow oxygenation devices.

A special oropharyngeal oxygenation device to facilitate apneic oxygenation in comparison to high flow oxygenation devices.

A special oropharyngeal oxygenation device to facilitate apneic oxygenation in comparison to high flow oxygenation devices.

Oxygen application and apneic oxygenation may reduce the risk of hypoxemia due to apnea during awake fiberoptic intubation or failed endotracheal intubation. High flow devices are recommended, but their effect compared to moderate deep oropharyngeal oxygen application is unknown. Designed as an experimental manikin trial, we made a comparison between oxygen application via nasal prongs at 10 L/min (control group), applying oxygen via oropharyngeal oxygenation device (at 10 L/min), oxygen application via high flow nasal oxygen with 20 L/min and 90% oxygen (20 L/90% group), oxygen application via high flow nasal oxygen with 60 L/min and 45% oxygen (60 L/45% group), and oxygen application via sealed face mask with a special adapter to allow for fiberoptic entering of the airway. We preoxygenated the lung of a manikin and measured the decrease in oxygen level during the following 20 minutes for each way of oxygen application. Oxygen levels fell from 97 ± 1% at baseline to 75 ± 1% in control group, and to 86 ± 1% in oropharyngeal oxygenation device group. In the high flow nasal oxygen group, oxygen level dropped to 72 ± 1% in the 20 L/90% group and to 44 ± 1% in the 60 L/45% group. Oxygen level remained at 98 ± 0% in the face mask group. In conclusion, in this manikin simulation study of apneic oxygenation, oxygen insufflation using a sealed face mask kept oxygen levels in the test lung at 98% over 20 minutes, oral oxygenation device led to oxygen levels at 86%, whereas all other methods resulted in the decrease of oxygen levels below 75%.

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来源期刊
Medical Gas Research
Medical Gas Research MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
5.10
自引率
13.80%
发文量
35
期刊介绍: Medical Gas Research is an open access journal which publishes basic, translational, and clinical research focusing on the neurobiology as well as multidisciplinary aspects of medical gas research and their applications to related disorders. The journal covers all areas of medical gas research, but also has several special sections. Authors can submit directly to these sections, whose peer-review process is overseen by our distinguished Section Editors: Inert gases - Edited by Xuejun Sun and Mark Coburn, Gasotransmitters - Edited by Atsunori Nakao and John Calvert, Oxygen and diving medicine - Edited by Daniel Rossignol and Ke Jian Liu, Anesthetic gases - Edited by Richard Applegate and Zhongcong Xie, Medical gas in other fields of biology - Edited by John Zhang. Medical gas is a large family including oxygen, hydrogen, carbon monoxide, carbon dioxide, nitrogen, xenon, hydrogen sulfide, nitrous oxide, carbon disulfide, argon, helium and other noble gases. These medical gases are used in multiple fields of clinical practice and basic science research including anesthesiology, hyperbaric oxygen medicine, diving medicine, internal medicine, emergency medicine, surgery, and many basic sciences disciplines such as physiology, pharmacology, biochemistry, microbiology and neurosciences. Due to the unique nature of medical gas practice, Medical Gas Research will serve as an information platform for educational and technological advances in the field of medical gas.
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